Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651322 | 0.81 | KMT2A (0.53) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL28254520 | 0.75 | CA1 (0.55) | MAPTCDK2CDK1ROCK1 | |
| SCHEMBL2530028 | 0.74 | MEN1 (0.50) | MAPTRAB9ANPC1PIM1MEN1 | |
| SCHEMBL2648161 | 0.73 | FABP1 (0.61) | MAPTRAB9AMAPK1NPC1MEN1 | |
| SCHEMBL29582475 | 0.73 | MEN1 (0.64) | MAPTRAB9AMAPK1CDK2NPC1 | |
| SCHEMBL626575 | 0.73 | MEN1 (0.64) | MAPTRAB9AMAPK1CDK2NPC1 | |
| SCHEMBL31138002 | 0.71 | MEN1 (0.61) | MAPTRAB9AMAPK1CDK2NPC1 | |
| SCHEMBL71629 | 0.71 | MAPT (0.47) | MAPTRAB9AMAPK1CDK2NPC1 | |
| SCHEMBL149380 | 0.71 | MEN1 (0.55) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1901811 | 0.70 | KDM4E (0.49) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138395-B2 | Interleukin-1β converting enzyme inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2006-11-21 | — | — | US | disclosed |