SCHEMBL149380

SCHEMBL149380

[c]1ccc(Nc2ccccn2)cc1

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
MAPK10 P53779 1/20 0.55
GFER P55789 1/20 0.55
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
GAA P10253 1/20 0.44
ADRA2A P08913 2/20 0.43
ADRA2B P18089 2/20 0.43
ADRA2C P18825 2/20 0.43
KDR P35968 4/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4727244 0.85
SCHEMBL626575 0.83 MEN1 (0.64) MEN1KMT2AMAPK10GFERALDH1A1
SCHEMBL29582475 0.83 MEN1 (0.64) MEN1KMT2AMAPK10GFERALDH1A1
SCHEMBL31138002 0.81 MEN1 (0.61) MEN1KMT2AMAPK10GFERALDH1A1
SCHEMBL2530028 0.79 MEN1 (0.50) MEN1KMT2AMAPK10GFERALDH1A1
SCHEMBL31390266 0.79 MEN1 (0.59) MEN1KMT2AMAPK10GFERALDH1A1
SCHEMBL2840729 0.79 MEN1 (0.59) MEN1KMT2AMAPK10GFERALDH1A1
Water SCHEMBL28126483 0.78 KMT2A (0.70) MEN1KMT2AMAPK10GFERALDH1A1
SCHEMBL221242 0.78 KMT2A (0.76) MEN1KMT2AMAPK10GFERALDH1A1
SCHEMBL29391624 0.78 KMT2A (0.76) MEN1KMT2AMAPK10GFERALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344142-B2 perylenetetracarboxylic diimide core having side chains (groups or mesogens) attached to the core; to provide charge-transport materials having various volatilities, solubilities, crystallinity, and charge transport ability; organic light emitting diode; photovoltaic cells, light-emitting diodes GEORGIA TECH RESEARCH CORPORATION (US) 2013-01-01 US claimed
US-8039625-B2 Coronene charge-transport materials, methods of fabrication thereof, and methods of use thereof GEORGIA TECH RESEARCH CORPORATION (US) 2011-10-18 US claimed
US-20090044863-A1 CORONENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF NATIONAL SCIENCE FOUNDATION 2009-02-19 US claimed
US-20080223444-A1 Perylene Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof GEORGIA TECH RESEARCH CORPORATION 2008-09-18 US claimed
WO-2006093965-A2 CORONENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2006-09-08 WO claimed
WO-2005124453-A2 PERYLENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2005-12-29 WO claimed
CN-113330096-B Use of substituted or unsubstituted polycyclic aromatic compounds for high resolution microscopy 马克斯·普朗克索赔科学公司 2024-05-31 CN disclosed
US-11958796-B2 Hydrophilic and particularly water soluble DBOV-derivatives MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-04-16 US disclosed
CN-112839922-B Hydrophilic and in particular water-soluble DBOV derivatives 马克斯·普朗克索赔科学公司 2024-04-02 CN disclosed
EP-3830217-B1 USE OF A SUBSTITUTED OR UNSUBSTITUTED POLYCYCLIC AROMATIC HYDROCARBON COMPOUND FOR HIGH-RESOLUTION MICROSCOPY MAX PLANCK GESELLSCHAFT (DE) 2022-07-20 EP disclosed
US-20220009870-A1 HYDROPHILIC AND PARTICULARLY WATER SOLUBLE DBOV-DERIVATIVES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2022-01-13 US disclosed
US-20210388260-A1 USE OF A SUBSTITUTED OR UNSUBSTITUTED POLYCYCLIC AROMATIC HYDROCARBON COMPOUND FOR HIGH-RESOLUTION MICROSCOPY Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V (DE) 2021-12-16 US disclosed
CN-113330096-A Use of substituted or unsubstituted polycyclic aromatic hydrocarbon compounds for high resolution microscopy 马克斯·普朗克索赔科学公司 2021-08-31 CN disclosed
US-5808073-A CATALYTIC AMINATION OF THE CORRESPONDING PERYLENETETRACARBOXYLIC ACID OR ANHYDRIDE WITH PRIMARY AMINE IN TERTIARY AMINE SOLVENT BASF AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed
CN-1169155-A Substituted transannular tetracarboxylic acid diimide BASF AG (DE) 1997-12-31 CN disclosed
CN-1168151-A Process for producing and purifying perylene-3,4-dicarboxylic acid imides BASF AG (DE) 1997-12-17 CN disclosed
EP-0804508-A1 PROCESS FOR PRODUCING AND PURIFYING PERYLENE-3,4-DICARBOXYLIC ACID IMIDES BASF AKTIENGESELLSCHAFT (DE) 1997-11-05 EP disclosed
EP-0804507-A1 SUBSTITUTED QUATERRYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 1997-11-05 EP disclosed
WO-1996022332-A1 SUBSTITUTED QUATERRYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 1996-07-25 WO disclosed
WO-1996022331-A1 PROCESS FOR PRODUCING AND PURIFYING PERYLENE-3,4-DICARBOXYLIC ACID IMIDES BASF AKTIENGESELLSCHAFT (DE) 1996-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220009870-A1 HYDROPHILIC AND PARTICULARLY WATER SOLUBLE DBOV-DERIVATIVES NR1H4, HDGF, ABHD16A MEN1 3433/4885KMT2A 2368/4885MAPK10 4660/4885
US-20210388260-A1 USE OF A SUBSTITUTED OR UNSUBSTITUTED POLYCYCLIC AROMATIC HYDROCARBON COMPOUND FOR HIGH-RESOLUTION MICROSCOPY AHR, ARNT, SAMM50 MEN1 897/4885KMT2A 1176/4885MAPK10 2664/4885
US-11958796-B2 Hydrophilic and particularly water soluble DBOV-derivatives NR1H4, HDGF, ABHD16A MEN1 3433/4885KMT2A 2368/4885MAPK10 4660/4885
US-20080223444-A1 Perylene Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof SLC43A1, SLC3A2, SLC16A3 MEN1 1319/4885KMT2A 2311/4885MAPK10 4324/4885
US-20090044863-A1 CORONENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF SLC18A3, CORO1C, SLC18A1 MEN1 2368/4885KMT2A 4342/4885MAPK10 2416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.