Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 10/20 | 0.57 |
| ▸ | PTGES | O14684 | 5/20 | 0.57 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | EDNRB | P24530 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092353 | 0.88 | SERPINE1 (0.56) | PTGES2PTGESSERPINE1TBXAS1EDNRB | |
| SCHEMBL6093339 | 0.86 | SERPINE1 (0.61) | PTGES2PTGESSERPINE1EDNRBEDNRA | |
| SCHEMBL14117729 | 0.84 | SERPINE1 (0.56) | SERPINE1EDNRBEDNRAMEN1KMT2A | |
| SCHEMBL14117727 | 0.77 | PTGDR2 (0.53) | PTGES2PTGESSERPINE1EDNRBEDNRA | |
| SCHEMBL27605863 | 0.76 | PTGDR2 (0.72) | PTGES2PTGESAKR1B1PTGDR2 | |
| SCHEMBL6093097 | 0.76 | SERPINE1 (0.51) | PTGES2PTGESSERPINE1TBXAS1PPARG | |
| SCHEMBL6092255 | 0.76 | ICMT (0.48) | PTGES2PTGESSERPINE1TBXAS1PPARG | |
| SCHEMBL4980145 | 0.76 | SERPINE1 (0.81) | SERPINE1EDNRBEDNRAMEN1KMT2A | |
| SCHEMBL21465578 | 0.75 | PTGES2 (0.53) | PTGES2PTGESSERPINE1TBXAS1MEN1 | |
| SCHEMBL5172732 | 0.75 | SERPINE1 (0.60) | SERPINE1EDNRBEDNRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | PTGES2 6/4885PTGES 4/4885SERPINE1 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.