Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 18/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732152 | 0.91 | HMGCR (0.56) | HMGCR | |
| SCHEMBL6090615 | 0.89 | HMGCR (0.49) | HMGCR | |
| SCHEMBL6091718 | 0.88 | HMGCR (0.41) | HMGCR | |
| SCHEMBL5732374 | 0.83 | HMGCR (0.53) | HMGCR | |
| SCHEMBL6091508 | 0.81 | MEN1 (0.44) | HMGCR | |
| SCHEMBL5731420 | 0.79 | HMGCR (0.45) | HMGCR | |
| SCHEMBL5731592 | 0.77 | HMGCR (0.43) | HMGCR | |
| SCHEMBL5731225 | 0.77 | HMGCR (0.56) | HMGCR | |
| SCHEMBL5731467 | 0.77 | HMGCR (0.52) | HMGCR | |
| SCHEMBL6090595 | 0.76 | HMGCR (0.43) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006059210-A2 | FUSED BICYCLIC PYRROLS AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-08 | — | — | WO | disclosed |