Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.56 |
| ▸ | F10 | P00742 | 4/20 | 0.54 |
| ▸ | CCR2 | P41597 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CCR9 | P51686 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307843 | 0.87 | NOD2 (0.74) | NOD2NOD1F10CCR2MAPT | |
| SCHEMBL6300916 | 0.86 | NOD2 (0.57) | NOD2NOD1F10CCR2MAPT | |
| SCHEMBL4414074 | 0.81 | NOD2 (0.65) | NOD2NOD1F10CCR2MAPT | |
| SCHEMBL4091859 | 0.80 | KMT2A (0.47) | NOD2NOD1F10CCR2MAPT | |
| SCHEMBL4099860 | 0.80 | MAPT (0.56) | NOD2NOD1F10CCR2MAPT | |
| SCHEMBL12930101 | 0.80 | NOD2 (0.67) | NOD2NOD1F10MAPTCCR9 | |
| SCHEMBL1503984 | 0.80 | NOD2 (0.67) | NOD2NOD1F10CCR2MAPT | |
| SCHEMBL3201430 | 0.79 | NOD2 (0.63) | NOD2NOD1F10CCR2MAPT | |
| SCHEMBL21822412 | 0.79 | NOD2 (0.54) | NOD2NOD1F10MAPTCCR9 | |
| SCHEMBL940391 | 0.79 | F10 (0.54) | NOD2NOD1F10CCR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | NOD2 1316/4885NOD1 834/4885F10 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.