Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092418 | 0.83 | AOC3 (0.50) | AOC3UGT2B7SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28144244 | 0.78 | CHRNB2 (0.56) | AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5398515 | 0.78 | CHRNB2 (0.56) | AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28144242 | 0.78 | CHRNB2 (0.56) | AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12071516 | 0.78 | CHRNB2 (0.56) | AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9995387 | 0.78 | CHRNB2 (0.56) | AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12861377 | 0.78 | AOC3 (0.48) | AOC3UGT2B7SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20193367 | 0.77 | UGT2B7 (0.58) | AOC3UGT2B7SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3978356 | 0.77 | UGT2B7 (0.43) | AOC3UGT2B7SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL17710458 | 0.77 | CHRNB2 (0.54) | AOC3SLC6A2SLC6A4SLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | disclosed |