Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.48 |
| ▸ | HTR2A | P28223 | 8/20 | 0.48 |
| ▸ | HTR1A | P08908 | 7/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460865 | 0.87 | DRD2 (0.49) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL8338559 | 0.87 | DRD2 (0.49) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL12345546 | 0.85 | DRD2 (0.48) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| Hydrochloric Acid SCHEMBL1443956 | 0.85 | DRD2 (0.48) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL9910963 | 0.85 | DRD2 (0.48) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL5623016 | 0.85 | DRD2 (0.48) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL6493190 | 0.83 | SMN1; SMN2 (0.49) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL8235846 | 0.83 | DRD2 (0.47) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL8268654 | 0.82 | SMN1; SMN2 (0.42) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL11193250 | 0.82 | SMN1; SMN2 (0.51) | DRD2HTR2AHTR1AKCNH2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006046082-A1 | A PROCESS FOR THE PREPARATION OF RISPERIDONE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-05-04 | — | — | WO | claimed |
| US-9670200-B2 | Quaternary ammonium salt prodrugs | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |
| WO-2006046082-A1 | A PROCESS FOR THE PREPARATION OF RISPERIDONE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-05-04 | — | — | WO | disclosed |
| WO-2006046082-A1 | A PROCESS FOR THE PREPARATION OF RISPERIDONE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-05-04 | — | — | WO | disclosed |
| WO-2006046082-A1 | A PROCESS FOR THE PREPARATION OF RISPERIDONE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-05-04 | — | — | WO | disclosed |
| WO-2004043923-A1 | PROCESS FOR MAKING RISPERIDONE AND INTERMEDIATES THEREFOR | SYNTHON B.V. (NL) | 2004-05-27 | — | — | WO | disclosed |