Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.83 |
| ▸ | CES2 | O00748 | 1/20 | 0.83 |
| ▸ | CA1 | P00915 | 4/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223704 | 0.91 | CES1 (1.00) | CES1CES2CA1CA2BCHE | |
| Water SCHEMBL9045475 | 0.89 | CES1 (0.96) | CES1CES2CA1CA2BCHE | |
| SCHEMBL11588711 | 0.89 | CES1 (0.96) | CES1CES2CA1CA2BCHE | |
| Bromide SCHEMBL11420868 | 0.89 | CES1 (0.96) | CES1CES2CA1CA2BCHE | |
| SCHEMBL11588705 | 0.89 | CES1 (0.96) | CES1CES2CA1CA2BCHE | |
| SCHEMBL5246741 | 0.84 | CES1 (0.86) | CES1CES2CA1CA2BCHE | |
| SCHEMBL4823833 | 0.84 | CES2 (0.80) | CES1CES2CA1CA2BCHE | |
| SCHEMBL233887 | 0.84 | CES2 (0.86) | CES1CES2CA1CA2BCHE | |
| SCHEMBL2040099 | 0.84 | CES2 (0.80) | CES1CES2CA1CA2BCHE | |
| SCHEMBL4816750 | 0.84 | CES1 (0.80) | CES1CES2CA1CA2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763890-B2 | Bacterial ghosts as carrier and targeting vehicles | WERNER LUBITZ (AT) | 2017-09-19 | — | — | US | disclosed |
| US-20160220499-A1 | BACTERIAL GHOSTS AS CARRIER AND TARGETING VEHICLES | Lubitz, Werner (AT) | 2016-08-04 | — | — | US | disclosed |
| US-20120040829-A1 | BACTERIAL GHOSTS AS CARRIER AND TARGETING VEHICLES | Lubitz, Werner (AT) | 2012-02-16 | — | — | US | disclosed |
| US-20030166568-A1 | Organic compounds | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2003-09-04 | — | — | US | disclosed |
| EP-1158966-B1 | LOADED BACTERIAL GHOSTS AS CARRIER AND TARGETING VEHICLES | LUBITZ WERNER (AT) | 2003-06-11 | — | — | EP | disclosed |
| EP-1269198-A2 | IDENTIFICATION OF MAST/BASOPHIL ACTIVATION INHIBITORS | Novartis AG (CH) | 2003-01-02 | — | — | EP | disclosed |
| EP-1158966-A1 | BACTERIAL GHOSTS AS CARRIER AND TARGETING VEHICLES | Lubitz, Werner, Dr. (AT) | 2001-12-05 | — | — | EP | disclosed |
| WO-2001071342-A2 | IDENTIFICATION OF MAST CELL/BASOPHIL ACTIVATION INHIBITORS | NOVARTIS AG (CH) | 2001-09-27 | — | — | WO | disclosed |
| WO-2000053163-A1 | BACTERIAL GHOSTS AS CARRIER AND TARGETING VEHICLES | LUBITZ WERNER (AT) | 2000-09-14 | — | — | WO | disclosed |
| US-5350677-A | Sampling and reaction, measuring color | IATRON LABORATORIES, INC. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0411159-A1 | METHOD FOR DETERMINING ENZYMATIC ACTIVITY | IATRON LABORATORIES, INC. (JP) | 1991-02-06 | — | — | EP | disclosed |