Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752084 | 0.90 | ALDH1A1 (0.39) | SMN1; SMN2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL1142569 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL15105602 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL2185965 | 0.82 | CYP4F2 (0.40) | SMN1; SMN2POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL17454 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL8394595 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL8391610 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL16838736 | 0.81 | CYP1A2 (0.38) | SMN1; SMN2POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL2123 | 0.81 | CYP1A2 (0.38) | SMN1; SMN2POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL17162705 | 0.80 | POLB (0.39) | SMN1; SMN2POLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006064286-A1 | CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006064286-A1 | CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2006-06-22 | — | — | WO | disclosed |