Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070036 | 0.87 | CYP3A4 (0.53) | CYP3A4USP2MAPTESR1ESR2 | |
| SCHEMBL2070035 | 0.87 | CYP3A4 (0.53) | CYP3A4USP2MAPTESR1ESR2 | |
| SCHEMBL7500860 | 0.87 | CYP3A4 (0.53) | CYP3A4USP2MAPTESR1ESR2 | |
| SCHEMBL24103712 | 0.86 | ESR1 (0.50) | CYP3A4CYP19A1SMN1; SMN2MAPTESR1 | |
| SCHEMBL17965954 | 0.86 | ESR1 (0.50) | CYP3A4CYP19A1SMN1; SMN2MAPTESR1 | |
| SCHEMBL30362774 | 0.86 | ESR1 (0.50) | CYP3A4CYP19A1SMN1; SMN2MAPTESR1 | |
| SCHEMBL242969 | 0.86 | ESR1 (0.50) | CYP3A4CYP19A1SMN1; SMN2MAPTESR1 | |
| SCHEMBL6093567 | 0.85 | CYP3A4 (0.50) | CYP3A4CYP19A1ESR1ESR2MAOA | |
| SCHEMBL24103707 | 0.84 | ESR1 (0.55) | CYP3A4CYP19A1SMN1; SMN2MAPTESR1 | |
| SCHEMBL17965956 | 0.84 | ESR1 (0.55) | CYP3A4CYP19A1SMN1; SMN2MAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060217564-A1 | Production of isoflavone derivatives | NOVOGEN RESEARCH PTY LTD. | 2006-09-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217564-A1 | Production of isoflavone derivatives | CYP51A1, EGLN2, EGLN3 | CYP3A4 14/4885CYP19A1 5/4885USP2 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.