Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.54 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563358 | 0.87 | ALOX15 (0.55) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL3960481 | 0.82 | CYP3A4 (0.54) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL14338684 | 0.82 | ALOX15 (0.41) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL14338687 | 0.80 | ALOX15 (0.46) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL10561540 | 0.80 | ALOX15 (0.66) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL19418881 | 0.79 | ALOX15 (0.72) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL31545514 | 0.77 | ESR1 (0.72) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL8983930 | 0.76 | ALOX15 (0.48) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL14374110 | 0.76 | ESR1 (0.55) | ESR1ESR2TTRALOX15ALOX12 | |
| Aus-131 SCHEMBL17591903 | 0.76 | ESR2 (0.83) | ESR1ESR2TTRALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143588-A1 | Production of isoflavone derivatives | NOVOGEN RESEARCH PTY LTD. | 2005-06-30 | — | — | US | claimed |
| EP-1153020-A4 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RES PTY LTD (AU) | 2002-08-21 | — | — | EP | claimed |
| EP-1153020-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | Novogen Research Pty. Ltd. (AU) | 2001-11-14 | — | — | EP | claimed |
| WO-2000049009-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RESEARCH PTY. LTD. (AU) | 2000-08-24 | — | — | WO | claimed |
| EP-3191464-B1 | SYNTHESIS OF ISOFLAVANES AND INTERMEDIATES THEREOF | SYSTEM BIOLOGIE AG (CH) | 2019-11-06 | — | — | EP | disclosed |
| US-10030003-B2 | Synthesis of isoflavanes and intermediates thereof | SYSTEM BIOLOGIE AG (CH) | 2018-07-24 | — | — | US | disclosed |
| US-10030003-B2 | Synthesis of isoflavanes and intermediates thereof | SYSTEM BIOLOGIE AG (CH) | 2018-07-24 | — | — | US | disclosed |
| US-20170283389-A1 | Synthesis of Isoflavanes and Intermediates Thereof | SYSTEM BIOLOGIE AG (CH) | 2017-10-05 | — | — | US | disclosed |
| US-20170283389-A1 | Synthesis of Isoflavanes and Intermediates Thereof | SYSTEM BIOLOGIE AG (CH) | 2017-10-05 | — | — | US | disclosed |
| US-20060217564-A1 | Production of isoflavone derivatives | NOVOGEN RESEARCH PTY LTD. | 2006-09-28 | — | — | US | disclosed |
| US-20050143588-A1 | Production of isoflavone derivatives | NOVOGEN RESEARCH PTY LTD. | 2005-06-30 | — | — | US | disclosed |
| EP-1153020-A4 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RES PTY LTD (AU) | 2002-08-21 | — | — | EP | disclosed |
| EP-1153020-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | Novogen Research Pty. Ltd. (AU) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000049009-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RESEARCH PTY. LTD. (AU) | 2000-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217564-A1 | Production of isoflavone derivatives | CYP51A1, EGLN2, EGLN3 | ESR1 232/4885ESR2 156/4885TTR 3514/4885 |
| US-10030003-B2 | Synthesis of isoflavanes and intermediates thereof | CYP4B1, CYP51A1, CYP4A11 | ESR1 186/4885ESR2 311/4885TTR 4347/4885 |
| US-20170283389-A1 | Synthesis of Isoflavanes and Intermediates Thereof | CYP4B1, CYP51A1, CYP4A11 | ESR1 186/4885ESR2 311/4885TTR 4347/4885 |
| US-20050143588-A1 | Production of isoflavone derivatives | CYP51A1, EGLN2, EGLN3 | ESR1 232/4885ESR2 156/4885TTR 3514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.