Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Carbromal. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbromal SCHEMBL8429924 | 1.00 | CRBN (0.37) | CRBNNR3C1MAPTRAB9ANPSR1 | |
| Carbromal SCHEMBL4351621 | 0.98 | CRBN (0.39) | CRBNNR3C1MAPTRAB9ANPSR1 | |
| Carbromal SCHEMBL261 | 0.98 | CRBN (0.39) | CRBNNR3C1MAPTRAB9ANPSR1 | |
| Carbromal SCHEMBL15057476 | 0.98 | CRBN (0.39) | CRBNNR3C1MAPTRAB9ANPSR1 | |
| Carbromal SCHEMBL14637724 | 0.96 | CRBN (0.37) | CRBNNR3C1MAPTRAB9ANPSR1 | |
| Carbromal SCHEMBL1537494 | 0.96 | CRBN (0.37) | CRBNNR3C1MAPTRAB9ANPSR1 | |
| Carbromal SCHEMBL1317120 | 0.96 | CRBN (0.37) | CRBNNR3C1MAPTRAB9ANPSR1 | |
| Carbromal SCHEMBL2025221 | 0.96 | CRBN (0.37) | CRBNNR3C1MAPTRAB9ANPSR1 | |
| Carbromal SCHEMBL59106 | 0.96 | CRBN (0.37) | CRBNNR3C1MAPTRAB9ANPSR1 | |
| Carbromal SCHEMBL4352660 | 0.96 | CRBN (0.37) | CRBNNR3C1MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3545023-B1 | PENTABLOCK COPOLYMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-11-04 | — | — | EP | claimed |
| US-10781279-B2 | Pentablock copolymers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-09-22 | — | — | US | claimed |
| US-20190322788-A1 | PENTABLOCK COPOLYMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2019-10-24 | — | — | US | claimed |
| EP-3545023-A1 | PENTABLOCK COPOLYMERS | 3M Innovative Properties Company (US) | 2019-10-02 | — | — | EP | claimed |
| WO-2018098023-A1 | PENTABLOCK COPOLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-31 | — | — | WO | claimed |
| US-4921930-A | ABRASION RESISTANT POLYESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-01 | — | — | US | claimed |
| EP-0309249-A2 | Acryloyloxy and methacryloyloxy group-containing condensation polymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-03-29 | — | — | EP | claimed |
| US-20240066473-A1 | Articles Including an Isoporous Membrane Disposed on a Porous Substrate and Methods of Making the Same | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2024-02-29 | — | — | US | disclosed |
| CN-111100439-B | Weather resistant transparent high heat polycarbonate copolymer compositions | 高新特殊工程塑料全球技术有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-109983059-B | Pentablock copolymers | 3M创新有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-113727961-A | Dicarboxylic acids, process for producing the same, and use thereof | 大阪燃气化学有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-11167251-B2 | Porous membranes including pentablock copolymers and method of making the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-11-09 | — | — | US | disclosed |
| EP-3545023-B1 | PENTABLOCK COPOLYMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-11-04 | — | — | EP | disclosed |
| US-4339433-A | SODIUM SALTS OF POLYMERS | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1982-07-13 | — | — | US | disclosed |
| US-4327012-A | POYESTER AND AN ACRYLONITRILE STYRENE POLYMER | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4304709-A | AROMATIC POLYESTER, POLYMER OF METHYL METHACRYLATE, BUTADIENE, AND STYRENE | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-12-08 | — | — | US | disclosed |
| EP-0030414-A1 | Thermoplastic polymer compositions and shaped articles formed therefrom | OCCIDENTAL CHEMICAL CORPORATION (US) | 1981-06-17 | — | — | EP | disclosed |
| EP-0007171-A1 | Polymer compositions, molded articles and films with improved hydrolytic stability | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4035344-A | Process for preparing ordered aromatic copolyamide urea polymer | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1977-07-12 | — | — | US | disclosed |
| US-3960818-A | Ordered aromatic copolyamide urea polymer | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1976-06-01 | — | — | US | disclosed |