Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BCL6 | P41182 | 1/20 | 0.42 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096925 | 0.88 | MAPT (0.60) | MAPTALDH1A1TSHRTDP1PKM | |
| SCHEMBL8099339 | 0.86 | MAPT (0.58) | MAPTALDH1A1TSHRTDP1PKM | |
| SCHEMBL10889416 | 0.84 | MAPT (0.56) | MAPTALDH1A1TSHRTDP1PKM | |
| SCHEMBL29843484 | 0.83 | MAPT (0.58) | MAPTALDH1A1TSHRTDP1PKM | |
| SCHEMBL112262 | 0.83 | MAPT (0.58) | MAPTALDH1A1TSHRTDP1PKM | |
| SCHEMBL23909 | 0.82 | MAPT (0.51) | MAPTALDH1A1TSHRTDP1PKM | |
| SCHEMBL10537989 | 0.82 | MAPT (0.55) | MAPTALDH1A1TSHRTDP1PKM | |
| SCHEMBL10614428 | 0.82 | MAPT (0.52) | MAPTALDH1A1TSHRTDP1PKM | |
| SCHEMBL29378395 | 0.82 | MAPT (0.51) | MAPTALDH1A1TSHRTDP1PKM | |
| SCHEMBL10758961 | 0.81 | MAPT (0.54) | MAPTALDH1A1TSHRPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| EP-1286953-B1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | disclosed |
| EP-1286953-A1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002079144-A1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | WO | disclosed |
| EP-0688767-A1 | 5-mercapto-2-nitro paraphenylenediamine compounds and hair dye compositions containing same | Bristol-Myers Squibb Company (US) | 1995-12-27 | — | — | EP | disclosed |
| US-5026401-A | Hair dyes | L'OREAL (FR) | 1991-06-25 | — | — | US | disclosed |
| US-4704474-A | RED-TO-VIOLET DIRECT DYES | WELLA AKTIENGESELLSCHAFT (DE) | 1987-11-03 | — | — | US | disclosed |
| EP-0132568-B1 | DERIVATIVES OF 1,4-DIAMINO-5-CHLORO-2-NITROBENZENE, PROCESS FOR THEIR PRODUCTION AND AGENTS FOR DYEING HAIR | Wella Aktiengesellschaft (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0203446-A1 | Nitro-p-phenylene diamine derivatives, process for their preparation and hair dye compositions containing these compounds | Wella Aktiengesellschaft (DE) | 1986-12-03 | — | — | EP | disclosed |
| EP-0132568-A1 | Derivatives of 1,4-diamino-5-chloro-2-nitrobenzene, process for their production and agents for dyeing hair | Wella Aktiengesellschaft (DE) | 1985-02-13 | — | — | EP | disclosed |
| US-3973900-A | AMINO NITRO BENZENES | WELLA AG (DT) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | KRT18, ALDH7A1, IK | MAPT 666/4885ALDH1A1 36/4885TSHR 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.