Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | BCL6 | P41182 | 3/20 | 0.53 |
| ▸ | BCOR | Q6W2J9 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843484 | 1.00 | MAPT (0.58) | MAPTALDH1A1BCL6BCORTSHR | |
| SCHEMBL8099339 | 0.94 | MAPT (0.58) | MAPTALDH1A1BCL6BCORTSHR | |
| SCHEMBL10613577 | 0.93 | MAPT (0.52) | MAPTALDH1A1BCL6BCORTSHR | |
| SCHEMBL11096925 | 0.92 | MAPT (0.60) | MAPTALDH1A1BCL6BCORTSHR | |
| SCHEMBL10613700 | 0.91 | BCL6 (0.63) | MAPTALDH1A1BCL6BCORTSHR | |
| SCHEMBL10614428 | 0.86 | MAPT (0.52) | MAPTALDH1A1BCL6BCORTSHR | |
| SCHEMBL10613571 | 0.85 | MAPT (0.45) | MAPTALDH1A1BCL6BCORTSHR | |
| SCHEMBL10889416 | 0.84 | MAPT (0.56) | MAPTALDH1A1BCL6BCORTSHR | |
| SCHEMBL6093795 | 0.83 | MAPT (0.55) | MAPTALDH1A1BCL6BCORTSHR | |
| SCHEMBL23909 | 0.83 | MAPT (0.51) | MAPTALDH1A1BCL6BCORTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 773 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437123-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | claimed |
| EP-0999823-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2011-10-05 | — | — | EP | claimed |
| EP-2263642-A2 | Colouring bleaches | Henkel AG & Co. KGaA (DE) | 2010-12-22 | — | — | EP | claimed |
| EP-1666095-B1 | Composition for simultaneous colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | OREAL (FR) | 2010-05-19 | — | — | EP | claimed |
| US-7452386-B2 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | L'OREAL S.A. (FR) | 2008-11-18 | — | — | US | claimed |
| EP-1437123-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2007-06-06 | — | — | EP | claimed |
| US-20060191080-A1 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | L'OREAL S.A. (FR) | 2006-08-31 | — | — | US | claimed |
| EP-1666095-A1 | Composition for simultanesou colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | Societe L'Oreal S.A. (FR) | 2006-06-07 | — | — | EP | claimed |
| EP-0999823-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-6712861-B2 | CATIONIC DIRECT DYE | L'OREAL S.A. (FR) | 2004-03-30 | — | — | US | claimed |
| US-20020004956-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | RONDEAU CHRISTINE (FR) | 2002-01-17 | — | — | US | claimed |
| US-5972044-A | Composition and method for dyeing keratin fibers | WELLA AG (DE) | 1999-10-26 | — | — | US | claimed |
| EP-0646108-B1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1998-10-14 | — | — | EP | claimed |
| EP-0867170-A2 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1998-09-30 | — | — | EP | claimed |
| US-5792221-A | DYEING GRAY TO WHITE HAIR BLUE THROUGH PURPLISH-BLUE SHADES; WATER SOLUBILITY; WASH- AND COLORFASTNESS; WEATHERPROOFING; SWEAT RESISTANCE | L'OREAL (FR) | 1998-08-11 | — | — | US | claimed |
| EP-0646109-B1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0673926-B1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | OREAL (FR) | 1997-04-09 | — | — | EP | claimed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | claimed |
| EP-0673926-A1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | L'OREAL (FR) | 1995-09-27 | — | — | EP | claimed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060191080-A1 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | KRT18, NOX4, NOX5 | MAPT 1040/4885ALDH1A1 1918/4885BCL6 2362/4885 |
| US-20020004956-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | KRT18, TUBB1, TUBB4B | MAPT 522/4885ALDH1A1 1091/4885BCL6 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.