Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096607 | 0.93 | HTR2A (0.42) | ALDH1A1KDM4EGAASMN1; SMN2HSD17B10 | |
| SCHEMBL6094927 | 0.82 | GAA (0.41) | ALDH1A1KDM4EGAASMN1; SMN2HSD17B10 | |
| SCHEMBL6095470 | 0.80 | HTR2A (0.46) | ALDH1A1KDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL6095452 | 0.79 | GAA (0.57) | ALDH1A1KDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL6096015 | 0.78 | HTR2A (0.41) | ALDH1A1KDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL6325057 | 0.78 | HSP90AA1 (0.42) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL5276390 | 0.77 | HTR2A (0.63) | ALDH1A1KDM4EGAASMN1; SMN2SIGMAR1 | |
| SCHEMBL6093813 | 0.76 | HTR2A (0.43) | ALDH1A1KDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL6096604 | 0.75 | HRH3 (0.41) | ALDH1A1KDM4EGAASMN1; SMN2HSD17B10 | |
| Fluorobenzene SCHEMBL27499110 | 0.74 | KDM4E (0.49) | ALDH1A1KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084143-B2 | N-(indolecarbonyl) piperazine derivatives | MERCK PATENT GMBH (DE) | 2006-08-01 | — | — | US | claimed |