Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 1.00 |
| ▸ | HTR2B | P41595 | 9/20 | 1.00 |
| ▸ | HTR2A | P28223 | 9/20 | 1.00 |
| ▸ | HTR1A | P08908 | 7/20 | 1.00 |
| ▸ | HTR1D | P28221 | 5/20 | 1.00 |
| ▸ | HTR6 | P50406 | 3/20 | 1.00 |
| ▸ | HTR1B | P28222 | 3/20 | 1.00 |
| ▸ | HTR4 | Q13639 | 2/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | HTR7 | P34969 | 2/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092065 | 1.00 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL5936562 | 1.00 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL30390274 | 1.00 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6092175 | 0.99 | HTR2C (0.98) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6093427 | 0.99 | HTR2C (0.98) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6095848 | 0.99 | HTR2C (0.98) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| Maleic Acid SCHEMBL6093195 | 0.90 | HTR2C (0.82) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| Fumaric Acid SCHEMBL6093200 | 0.90 | HTR2C (0.82) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL6104548 | 0.88 | HTR2C (0.78) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL6104539 | 0.88 | HTR2C (0.78) | HTR2CHTR2BHTR2AHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012090-B1 | such as 1-(2-aminopropyl)-3,7,8,9,-tetrahydro-pyrano-[3,2-e]indol-8-ol | ALCON, INC. (CH) | 2006-03-14 | — | — | US | claimed |
| EP-1268482-B1 | PYRANOINDOLES FOR TREATING GLAUCOMA | ALCON INC (CH) | 2003-09-24 | — | — | EP | claimed |
| EP-1268482-A1 | PYRANOINDOLES FOR TREATING GLAUCOMA | Alcon Universal, Ltd. (CH) | 2003-01-02 | — | — | EP | claimed |
| WO-2001070745-A1 | PYRANOINDOLES FOR TREATING GLAUCOMA | ALCON, INC. (CH) | 2001-09-27 | — | — | WO | claimed |