SCHEMBL6092065

SCHEMBL6092065

CC(N)Cc1c[nH]c2ccc3c(c12)CCCO3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 10/20 1.00
HTR2B P41595 9/20 1.00
HTR2A P28223 9/20 1.00
HTR1A P08908 7/20 1.00
HTR1D P28221 5/20 1.00
HTR6 P50406 3/20 1.00
HTR1B P28222 3/20 1.00
HTR4 Q13639 2/20 1.00
ADRA2A P08913 2/20 1.00
HTR7 P34969 2/20 1.00
ADRA2C P18825 1/20 1.00
ALDH1A1 P00352 1/20 0.51
MAPT P10636 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ADRB1 P08588 1/20 0.42
SLC6A2 P23975 1/20 0.42
HTR1E P28566 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5936562 1.00 HTR2C (1.00) HTR2CHTR2BHTR2AHTR1AHTR1D
SCHEMBL30390274 1.00 HTR2C (1.00) HTR2CHTR2BHTR2AHTR1AHTR1D
SCHEMBL6094978 1.00 HTR2C (1.00) HTR2CHTR2BHTR2AHTR1AHTR1D
Hydrochloric Acid SCHEMBL6092175 0.99 HTR2C (0.98) HTR2CHTR2BHTR2AHTR1AHTR1D
Hydrochloric Acid SCHEMBL6093427 0.99 HTR2C (0.98) HTR2CHTR2BHTR2AHTR1AHTR1D
Hydrochloric Acid SCHEMBL6095848 0.99 HTR2C (0.98) HTR2CHTR2BHTR2AHTR1AHTR1D
Maleic Acid SCHEMBL6093195 0.90 HTR2C (0.82) HTR2CHTR2BHTR2AHTR1AHTR1D
Fumaric Acid SCHEMBL6093200 0.90 HTR2C (0.82) HTR2CHTR2BHTR2AHTR1AHTR1D
SCHEMBL6104548 0.88 HTR2C (0.78) HTR2CHTR2BHTR2AHTR1AHTR1D
SCHEMBL6104539 0.88 HTR2C (0.78) HTR2CHTR2BHTR2AHTR1AHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2983473-A2 PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF ALS Mountain Llc (US) 2016-02-17 EP claimed
US-20140350064-A1 PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF ALS MOUNTAIN LLC 2014-11-27 US claimed
WO-2014144130-A2 PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF ALS MOUNTAIN LLC (US) 2014-09-18 WO claimed
US-20120183600-A1 NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS CHEN CHIEN-HUNG (US) 2012-07-19 US claimed
US-7012090-B1 such as 1-(2-aminopropyl)-3,7,8,9,-tetrahydro-pyrano-[3,2-e]indol-8-ol ALCON, INC. (CH) 2006-03-14 US claimed
EP-1268482-B1 PYRANOINDOLES FOR TREATING GLAUCOMA ALCON INC (CH) 2003-09-24 EP claimed
US-20250177354-A1 THERAPEUTIC COMBINATIONS, COMPOSITIONS, AND METHODS FOR DESIGNING AND PRODUCING ENTACTOGENIC MINDSTATES MINDSTATE DESIGN LABS INC (US) 2025-06-05 US disclosed
US-12303564-B2 Composite chitosan-tannin-active agent compositions and methods of making and using same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-05-20 US disclosed
WO-2023081837-A9 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-03-14 WO disclosed
WO-2023081837-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2023-05-11 WO disclosed
US-20220296720-A1 COMPOSITE CHITOSAN-TANNIN-ACTIVE AGENT COMPOSITIONS AND METHODS OF MAKING AND USING SAME WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-09-22 US disclosed
EP-2983473-A2 PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF ALS Mountain Llc (US) 2016-02-17 EP disclosed
US-20140350064-A1 PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF ALS MOUNTAIN LLC 2014-11-27 US disclosed
WO-2014144130-A2 PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF ALS MOUNTAIN LLC (US) 2014-09-18 WO disclosed
US-20120183600-A1 NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS CHEN CHIEN-HUNG (US) 2012-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250177354-A1 THERAPEUTIC COMBINATIONS, COMPOSITIONS, AND METHODS FOR DESIGNING AND PRODUCING ENTACTOGENIC MINDSTATES CNR2, CNR1, HTR6 HTR2C 5/4885HTR2B 15/4885HTR2A 12/4885
US-20220296720-A1 COMPOSITE CHITOSAN-TANNIN-ACTIVE AGENT COMPOSITIONS AND METHODS OF MAKING AND USING SAME TTPA, CHIA, CHIT1 HTR2C 3495/4885HTR2B 3176/4885HTR2A 2918/4885
US-12303564-B2 Composite chitosan-tannin-active agent compositions and methods of making and using same TTPA, CHIA, CHIT1 HTR2C 3495/4885HTR2B 3176/4885HTR2A 2918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.