SCHEMBL6095018

SCHEMBL6095018

CCCC/C(C)=C/CC=C(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SQLE Q14534 5/20 0.42
KMT2A Q03164 3/20 0.41
CNR1 P21554 2/20 0.38
CNR2 P34972 2/20 0.38
TRPV1 Q8NER1 2/20 0.38
TRPA1 O75762 1/20 0.38
INHA P05111 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
OPRM1 P35372 1/20 0.38
PPARG P37231 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
TRPV3 Q8NET8 1/20 0.38
TRPV4 Q9HBA0 1/20 0.38
TRPV2 Q9Y5S1 1/20 0.38
MEN1 O00255 2/20 0.38
CYP3A4 P08684 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6095021 1.00 SQLE (0.42) SQLEKMT2ACNR1CNR2TRPV1
SCHEMBL1305010 0.89 KMT2A (0.58) SQLEKMT2ACNR1CNR2TRPV1
SCHEMBL1305011 0.89 KMT2A (0.58) SQLEKMT2ACNR1CNR2TRPV1
SCHEMBL18879322 0.80 ALOX15 (0.35) SQLEKMT2ACNR1CNR2TRPV1
SCHEMBL3645607 0.79 TSHR (0.39) SQLEKMT2ACNR1CNR2TRPV1
SCHEMBL11424176 0.79 KMT2A (0.58) SQLEKMT2AMEN1CYP3A4ALOX15
SCHEMBL1781480 0.79 CES1 (0.39) SQLETRPV1TRPA1ALDH1A1CES1
SCHEMBL1781481 0.79 CES1 (0.39) SQLETRPV1TRPA1ALDH1A1CES1
SCHEMBL848585 0.79 TSHR (0.39) SQLEKMT2ACNR1CNR2TRPV1
SCHEMBL11424170 0.79 KMT2A (0.58) SQLEKMT2AMEN1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7012120-B2 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent HENKEL CORPORATION (US) 2006-03-14 US claimed
US-20050288458-A1 Reworkable thermosetting resin composition KLEMARCZYK PHILIP T 2005-12-29 US claimed
EP-1268457-A4 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORP (US) 2005-07-20 EP claimed
JP-2003529643-A 2003-10-07 JP claimed
US-20030073770-A1 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent Henkel IP & Holding GmbH (DE) 2003-04-17 US claimed
EP-1268457-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2003-01-02 EP claimed
WO-2001074798-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2001-10-11 WO claimed
US-7012120-B2 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent HENKEL CORPORATION (US) 2006-03-14 US disclosed
US-20050288458-A1 Reworkable thermosetting resin composition KLEMARCZYK PHILIP T 2005-12-29 US disclosed
EP-1268457-A4 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORP (US) 2005-07-20 EP disclosed
US-20030073770-A1 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent Henkel IP & Holding GmbH (DE) 2003-04-17 US disclosed
EP-1268457-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2003-01-02 EP disclosed
WO-2001074798-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2001-10-11 WO disclosed