Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5676779 | 0.84 | ALDH1A1 (0.68) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL134640 | 0.83 | MEN1 (0.67) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL4060800 | 0.83 | TDP1 (0.71) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL14195744 | 0.78 | MAPT (0.65) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL3913429 | 0.74 | ALDH1A1 (0.62) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL3498187 | 0.74 | ALDH1A1 (0.62) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL4140103 | 0.72 | MAPT (0.67) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL3499288 | 0.72 | MAPT (1.00) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL5118588 | 0.72 | MEN1 (0.53) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL3777713 | 0.71 | TDP1 (0.69) | MEN1KMT2AMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067527-B2 | Thienopyridine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1259515-B1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | TAKEDA PHARMACEUTICAL (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20040054183-A1 | Thienopyridine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| US-6653476-B2 | Antiinflammatory and antiarthritic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-25 | — | — | US | disclosed |
| US-20030130517-A1 | Thienopyridine derivatives , their production and use | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130517-A1 | Thienopyridine derivatives , their production and use | ALK, HRH2, TBXA2R | MEN1 4809/4885KMT2A 866/4885MAPT 3749/4885 |
| US-20040054183-A1 | Thienopyridine derivatives, their production and use | ALK, HRH2, TBXA2R | MEN1 4809/4885KMT2A 866/4885MAPT 3749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.