Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5289576 | 1.00 | MAPT (0.51) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL15841249 | 0.81 | MAPT (0.53) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL3652495 | 0.81 | MAPT (0.53) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL3652492 | 0.81 | MAPT (0.53) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL12757021 | 0.77 | MEN1 (0.49) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6746931 | 0.75 | MEN1 (0.60) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6746928 | 0.75 | MEN1 (0.60) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL3160770 | 0.75 | MAPT (0.56) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL3090738 | 0.75 | MAPT (0.56) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL333756 | 0.75 | MAPT (0.56) | MAPTMEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218689-B1 | ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1990-08-01 | — | — | EP | claimed |
| EP-0263209-A2 | Anthelmintic quinolinyl acylhydrazones | THE UPJOHN COMPANY (US) | 1988-04-13 | — | — | EP | claimed |
| WO-1986005982-A3 | ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-04-23 | — | — | WO | claimed |
| EP-0218689-A1 | ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES AND COMPOSITIONS. | UPJOHN CO (US) | 1987-04-22 | — | — | EP | claimed |
| WO-1986005982-A2 | ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | UPJOHN CO (US) | 1986-10-23 | — | — | WO | claimed |
| US-7112391-B2 | Electrophotographic organophotoreceptors with novel charge transport compounds | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2006-09-26 | — | — | US | disclosed |
| US-20050074683-A1 | Electrophotographic organophotoreceptors with novel charge transport compounds | SAMSUNG ELECTRONICS CO., LTD. | 2005-04-07 | — | — | US | disclosed |
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0218689-B1 | ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4870082-A | PARASITICIDES, NEMATOCIDES | THE UPJOHN COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0263209-A2 | Anthelmintic quinolinyl acylhydrazones | THE UPJOHN COMPANY (US) | 1988-04-13 | — | — | EP | disclosed |
| WO-1986005982-A3 | ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-04-23 | — | — | WO | disclosed |
| EP-0218689-A1 | ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES AND COMPOSITIONS. | UPJOHN CO (US) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005982-A2 | ANTHELMINTIC QUINOLINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | UPJOHN CO (US) | 1986-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050074683-A1 | Electrophotographic organophotoreceptors with novel charge transport compounds | SLC18A2, SLC43A1, SLC1A2 | MAPT 3401/4885MEN1 2704/4885KMT2A 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.