Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.62 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.62 |
| ▸ | XDH | P47989 | 1/20 | 0.62 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | FLT3 | P36888 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421382 | 0.86 | CYP1B1 (0.86) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL29845342 | 0.86 | CYP1B1 (0.86) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL27907057 | 0.85 | CYP1B1 (0.84) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| Methane SCHEMBL27890494 | 0.85 | CYP1B1 (0.84) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL2483636 | 0.84 | CYP1B1 (1.00) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL30365934 | 0.84 | CYP1B1 (1.00) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL29883103 | 0.84 | CYP1B1 (1.00) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL7605191 | 0.81 | CYP1B1 (0.72) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL14178914 | 0.80 | CYP1B1 (0.71) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| Velutin SCHEMBL5804380 | 0.79 | CYP1B1 (0.86) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009062-B2 | Process for the preparation of flavone derivatives | MERCK PATENT GMBH (DE) | 2006-03-07 | — | — | US | disclosed |
| EP-1355898-B1 | METHOD FOR PRODUCING FLAVONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-10-12 | — | — | EP | disclosed |
| US-20040059100-A1 | Process for the preparation of flavone derivatives | EUROPEAN BRAND PARTICIPATIONS SA (LU) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059100-A1 | Process for the preparation of flavone derivatives | HK2, MAP2K5, MAP2K4 | CYP1B1 263/4885CYP1A1 242/4885CYP1A2 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.