Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468017 | 0.83 | SMN1; SMN2 (0.72) | F2RL1SMN1; SMN2FFAR1ALDH1A1POLB | |
| SCHEMBL13041414 | 0.83 | F2RL1 (0.59) | F2RL1TAAR1CALM1SMN1; SMN2FFAR1 | |
| SCHEMBL1334 | 0.83 | SMN1; SMN2 (0.72) | F2RL1SMN1; SMN2FFAR1ALDH1A1POLB | |
| SCHEMBL834551 | 0.81 | TAAR1 (0.73) | F2RL1TAAR1CALM1MAOBIDO1 | |
| SCHEMBL7329940 | 0.81 | F2RL1 (0.85) | F2RL1TAAR1CALM1SMN1; SMN2FFAR1 | |
| SCHEMBL274471 | 0.79 | FFAR1 (0.81) | F2RL1FFAR1ALDH1A1POLBNFKB1 | |
| SCHEMBL498481 | 0.79 | F2RL1 (0.59) | F2RL1TAAR1CALM1FFAR1ALDH1A1 | |
| Carbon Monoxide SCHEMBL6905879 | 0.79 | SMN1; SMN2 (0.66) | F2RL1SMN1; SMN2FFAR1ALDH1A1POLB | |
| Carbon Monoxide SCHEMBL6904137 | 0.79 | SMN1; SMN2 (0.66) | F2RL1SMN1; SMN2FFAR1ALDH1A1POLB | |
| SCHEMBL9191247 | 0.79 | MAOB (0.58) | F2RL1TAAR1CALM1SMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110278711-A | TRICYCLIC SULFONES AS ROR GAMMA MODULATORS | 百时美施贵宝公司 | 2019-09-24 | — | — | CN | disclosed |
| US-6984639-B2 | Heterocyclic ketone and thioester compounds and uses | GPI NIL HOLDINGS, INC. (US) | 2006-01-10 | — | — | US | disclosed |
| US-6417209-B2 | NON-IMMUNOSUPPRESSIVE, PIPERIDINO OR PYRROLIDINO AMIDE DERIVATIVE HAS AN AFFINITY FOR AN FKBP-TYPE IMMUNOPHILIN, USEFUL FOR TREATING ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, PARKINSON'S DISEASE, AMYOTROPHIC LATERAL SCLEROSIS | GPI NIL HOLDINGS, INC. | 2002-07-09 | — | — | US | disclosed |
| US-6384056-B1 | COGNITION ACTIVATORS AND NERVE AND VISION DISORDERS | GPI NIL HOLDINGS, INC. | 2002-05-07 | — | — | US | disclosed |
| US-6274602-B1 | ADMINISTERING COMPOSTITIONS SUCH AS 3,3-DIMETHYL-1-((2S)-2-(5-(3-PYRIDYL) PENTANOYL)-1-PYRROLIDINE)-1, 2-PENTANEDIONE TO TREAT ALOPECIA OR PROMOTING HAIR GROWTH IN ANIMALS | GPI NIL HOLDINGS, INC. | 2001-08-14 | — | — | US | disclosed |
| US-6218424-B1 | FOR EFFECTING NEURONAL ACTIVITIES IN ANIMALS, INCLUDING TREATING NEUROLOGICAL DISORDERS | GPI NIL HOLDINGS, INC. | 2001-04-17 | — | — | US | disclosed |
| EP-0630899-A1 | CEPHEM COMPOUND, PROCESS FOR PRODUCING THE SAME, AND MEDICINE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-4049806-A | Cephalosporin type antibacterials | SYNTEX (U.S.A.) INC. (US) | 1977-09-20 | — | — | US | disclosed |