SCHEMBL7329940

SCHEMBL7329940

COc1ccc(CCC(=O)CCc2ccc(OC)cc2)cc1

nearest known ligand 0.85

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.85
FFAR1 O14842 2/20 0.62
ALDH1A1 P00352 1/20 0.62
POLB P06746 1/20 0.62
NFKB1 P19838 1/20 0.62
NFKB2 Q00653 1/20 0.62
RELA Q04206 1/20 0.62
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
SLC5A1 P13866 1/20 0.60
SLC5A2 P31639 1/20 0.60
ALOX5 P09917 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.58
FKBP1A P62942 1/20 0.55
TAAR1 Q96RJ0 1/20 0.55
CALM1 P0DP23 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24800806 0.93 F2RL1 (0.74) F2RL1FFAR1ALDH1A1NPC1RAB9A
SCHEMBL9404116 0.92 F2RL1 (1.00) F2RL1FFAR1ALDH1A1POLBNFKB1
SCHEMBL10759018 0.91 F2RL1 (0.72) F2RL1FFAR1ALDH1A1POLBNFKB1
SCHEMBL24799818 0.91 F2RL1 (0.72) F2RL1FFAR1ALDH1A1POLBNFKB1
SCHEMBL3994134 0.90 F2RL1 (0.77) F2RL1FFAR1ALDH1A1POLBNFKB1
SCHEMBL20610768 0.89 F2RL1 (0.70) F2RL1FFAR1ALDH1A1POLBNFKB1
SCHEMBL20221724 0.89 F2RL1 (0.70) F2RL1FFAR1ALDH1A1POLBNFKB1
SCHEMBL9096140 0.89 F2RL1 (0.74) F2RL1FFAR1ALDH1A1POLBNFKB1
SCHEMBL9216095 0.89 F2RL1 (0.74) F2RL1FFAR1ALDH1A1POLBNFKB1
SCHEMBL1295548 0.89 F2RL1 (0.74) F2RL1FFAR1ALDH1A1POLBNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180515-A A kind of synthetic method of N- [2- hydroxyl -2- (4- methoxyphenyl) ethyl] cinnamamide 苏利制药科技江阴有限公司 2019-01-11 CN claimed
CN-115542666-A Photosensitive resin composition for spacer and protective film 奇美实业股份有限公司 2022-12-30 CN disclosed
CN-107544208-B Negative photosensitive resin composition, spacer, protective film and liquid crystal display element 奇美实业股份有限公司 2022-05-31 CN disclosed
CN-105717743-B Photosensitive resin composition and application thereof 奇美实业股份有限公司 2021-12-21 CN disclosed
CN-105717747-B Photosensitive resin composition and application thereof 奇美实业股份有限公司 2021-12-21 CN disclosed
CN-113671791-A Black photosensitive resin composition, black pattern, color filter and liquid crystal display device 奇美实业股份有限公司 2021-11-19 CN disclosed
CN-112147842-A Black photosensitive resin composition, black pattern and liquid crystal display device 奇美实业股份有限公司 2020-12-29 CN disclosed
CN-106933032-B Black photosensitive resin composition and application thereof 奇美实业股份有限公司 2020-12-11 CN disclosed
CN-106569388-B Photosensitive resin composition for black matrix and application thereof 奇美实业股份有限公司 2020-12-04 CN disclosed
CN-111856877-A Photosensitive resin composition, spacer, protective film and liquid crystal display element 奇美实业股份有限公司 2020-10-30 CN disclosed
US-20080234320-A1 CURCUMIN ANALOGS WITH ANTI-TUMOR AND ANTI-ANGIOGENIC PROPERTIES EMORY UNIVERSITY 2008-09-25 US disclosed
US-7371766-B2 Curcumin analogs with anti-tumor and anti-angiogenic properties EMORY UNIVERSITY (US) 2008-05-13 US disclosed
US-7371766-B2 Curcumin analogs with anti-tumor and anti-angiogenic properties EMORY UNIVERSITY (US) 2008-05-13 US disclosed
EP-0771196-B1 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS LILLY CO ELI (US) 1999-12-08 EP disclosed
US-5717109-A CARBOXYCYCLOPROPYL GLYCINE DERIVATIVES; USEFUL FOR TREATMENT OF ACUTE OR CHRONIC NEURODEGENERATIVE CONDITIONS, AND AS ANTIPSYCHOTIC, ANTICONVULSANT, ANALGESIC, ANXIOLYTIC, ANTIDEPRESSANT AND ANTI-EMETIC AGENTS ELI LILLY AND COMPANY (US) 1998-02-10 US disclosed
US-5668146-A ANTIINFLAMMATORY AGENTS OR ANTIALLERGENS ABBOTT LABORATORIES (US) 1997-09-16 US disclosed
EP-0771196-A4 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS LILLY CO ELI (US) 1997-09-03 EP disclosed
EP-0771196-A1 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1997-05-07 EP disclosed
WO-1996007405-A1 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-03-14 WO disclosed
US-4552876-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS USV PHARMACEUTICAL CORP. (US) 1985-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234320-A1 CURCUMIN ANALOGS WITH ANTI-TUMOR AND ANTI-ANGIOGENIC PROPERTIES PGF, VEGFA, VHL F2RL1 3274/4885FFAR1 2203/4885ALDH1A1 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.