SCHEMBL609678

SCHEMBL609678

C=Cc1cccc(N(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 5/20 0.48
TSHR P16473 3/20 0.48
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 1/20 0.46
GSK3B P49841 1/20 0.45
RELA Q04206 1/20 0.42
APP P05067 3/20 0.42
HDAC8 Q9BY41 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NOTUM Q6P988 1/20 0.36
PTGS2 P35354 1/20 0.36
CYP2A6 P11509 1/20 0.35
CYP2A13 Q16696 1/20 0.35
MAT2A P31153 1/20 0.35
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22542507 0.84 HDAC1 (0.48) TP53TDP1ALDH1A1TSHRNPC1
SCHEMBL6291797 0.80 TP53 (0.47) TP53TDP1ALDH1A1TSHRNPC1
SCHEMBL17010910 0.80 TDP1 (0.47) TP53TDP1ALDH1A1TSHRNPC1
SCHEMBL8911108 0.80 ALDH1A1 (0.50) TP53ALDH1A1TSHRNPC1MAPT
Styrene SCHEMBL10623882 0.80 ALDH1A1 (0.64) TP53TDP1ALDH1A1TSHRNPC1
SCHEMBL21020669 0.79 TP53 (0.46) TP53TDP1ALDH1A1TSHRNPC1
SCHEMBL9781541 0.78 GSK3B (0.49) ALDH1A1TSHRNPC1MAPTMAPK1
SCHEMBL29740784 0.78 CYP2A6 (0.56) ALDH1A1TSHRNPC1MAPTMAPK1
SCHEMBL1039994 0.78 CYP2A6 (0.56) ALDH1A1TSHRNPC1MAPTMAPK1
SCHEMBL609647 0.78 TDP1 (0.44) TP53TDP1ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111522200-B Negative PSPI resin for 12-inch silicon wafer and preparation method and application thereof 中国科学院化学研究所 2021-07-27 CN claimed
CN-111522200-A Negative PSPI resin for 12-inch silicon wafer and preparation method and application thereof 中国科学院化学研究所 2020-08-11 CN claimed
US-20070056900-A1 Use of copolymers containing n-vinyl lactam for producing functionalized membranes BASF AKTIENGESELLSCHAFT (DE) 2007-03-15 US claimed
EP-1757667-A2 Adhesive composition and process for adhesion using the adhesive composition Bridgestone Corporation (JP) 2007-02-28 EP claimed
US-20070042115-A1 Manufacturing method for tire cord and adhesive material for tire cord BRIDGESTONE CORPORATION (JP) 2007-02-22 US claimed
US-20070037911-A1 Adhesive composition and process for adhesion using the adhesive composition BRIDGESTONE CORPORATION 2007-02-15 US claimed
EP-1667789-A2 USE OF COPOLYMERS CONTAINING N-VINYL LACTAM FOR PRODUCING FUNCTIONALIZED MEMBRANES BASF AKTIENGESELLSCHAFT (DE) 2006-06-14 EP claimed
EP-1657354-A1 MANUFACTURING METHOD FOR TIRE CORD AND ADHESIVE MATERIAL FOR TIRE CORD Bridgestone Corporation (JP) 2006-05-17 EP claimed
WO-2005032701-A2 USE OF COPOLYMERS CONTAINING N-VINYL LACTAM FOR PRODUCING FUNCTIONALIZED MEMBRANES BASF AKTIENGESELLSCHAFT (DE) 2005-04-14 WO claimed
US-20040149382-A1 Adhesive composition and method for bonding to rubber BRIDGESTONE CORPORATION (JP) 2004-08-05 US claimed
EP-1400577-A1 ADHESIVE COMPOSITIONS AND METHOD FOR BONDING TO RUBBER BRIDGESTONE CORPORATION (JP) 2004-03-24 EP claimed
EP-4130185-B1 ADHESIVE COMPOSITION, ADHESIVE AGENT, ADHESIVE TAPE AND AIRTIGHT WATERPROOF ADHESIVE TAPE MITSUBISHI CHEM CORP (JP) 2024-10-23 EP disclosed
US-20240052109-A1 POLYSILOXANE VINYLIC MONOMERS AND USES THEREOF ALCON INC. (CH) 2024-02-15 US disclosed
US-11873364-B2 Method for producing conjugated diene rubber ZEON CORPORATION (JP) 2024-01-16 US disclosed
CN-114656397-B Compound, two-dimensional organic crystal containing compound, preparation method and application 中国科学院化学研究所 2023-07-25 CN disclosed
CN-87104996-A THERMOSTABLE PHOTOSENSITIVE AND CORROSION-RESISTANT FILM 1988-02-03 CN disclosed
EP-0193013-A2 Benzimidazolyl-pyridazinones MERCK PATENT GmbH (DE) 1986-09-03 EP disclosed
US-4551502-A Macromolecular complexes of amidocarbonylic water-soluble polymers and square platinous and equivalent organometallics HOWELL BOBBY A 1985-11-05 US disclosed
US-4405757-A Macromolecular complexes of amidocarbonylic water-soluble polymers and square planar platinous and equivalent organometallics HOWELL BOBBY A 1983-09-20 US disclosed
US-4046577-A PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS THE RICHARDSON COMPANY (US) 1977-09-06 US disclosed