Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.51 |
| ▸ | KIFC1 | Q9BW19 | 5/20 | 0.50 |
| ▸ | ECE1 | P42892 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3991301 | 1.00 | ITGB1 (0.51) | ITGB1ITGA4KIFC1ECE1MRGPRX4 | |
| SCHEMBL4829787 | 1.00 | ITGB1 (0.51) | ITGB1ITGA4KIFC1ECE1MRGPRX4 | |
| SCHEMBL3989525 | 1.00 | ITGB1 (0.51) | ITGB1ITGA4KIFC1ECE1MRGPRX4 | |
| SCHEMBL3972237 | 0.94 | KIFC1 (0.59) | ITGB1ITGA4KIFC1ECE1MRGPRX4 | |
| SCHEMBL4824086 | 0.94 | KIFC1 (0.59) | ITGB1ITGA4KIFC1ECE1MRGPRX4 | |
| SCHEMBL13986728 | 0.91 | PSMB5 (0.46) | ITGB1ITGA4KIFC1ECE1MCL1 | |
| SCHEMBL4827782 | 0.91 | ECE1 (0.53) | ITGB1ITGA4KIFC1ECE1ITGB7 | |
| SCHEMBL4827784 | 0.91 | ECE1 (0.53) | ITGB1ITGA4KIFC1ECE1ITGB7 | |
| SCHEMBL4827806 | 0.90 | CDK2 (0.47) | ITGB1ITGA4KIFC1ECE1MCL1 | |
| SCHEMBL5544392 | 0.90 | CDK2 (0.47) | ITGB1ITGA4KIFC1ECE1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |