Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCK1 | P35558 | 11/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097370 | 0.87 | PCK1 (0.38) | PCK1ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL3978694 | 0.85 | PCK1 (0.37) | PCK1CCR5 | |
| SCHEMBL6097396 | 0.85 | PCK1 (0.36) | PCK1CCR5 | |
| SCHEMBL3978683 | 0.85 | PCK1 (0.36) | PCK1 | |
| SCHEMBL3977456 | 0.85 | PCK1 (0.35) | PCK1ADORA3 | |
| SCHEMBL3979620 | 0.85 | PCK1 (0.39) | PCK1 | |
| SCHEMBL6097928 | 0.84 | PCK1 (0.39) | PCK1 | |
| SCHEMBL6097677 | 0.84 | PCK1 (0.35) | PCK1ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL3978799 | 0.83 | PCK1 (0.37) | PCK1 | |
| SCHEMBL6096610 | 0.83 | PCK1 (0.36) | PCK1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135475-B2 | Antidiabetic agents | HOFFMANN-LA ROCHE INC. (US) | 2006-11-14 | — | — | US | claimed |