Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Picolinic Acid SCHEMBL432468 | 0.98 | CES2 (0.64) | CES2CES1L3MBTL1LMNAP4HTM | |
| 2-Picolinic Acid SCHEMBL11378795 | 0.96 | CES2 (0.67) | CES2CES1L3MBTL1LMNAP4HTM | |
| 2-Picolinic Acid SCHEMBL524041 | 0.93 | CES2 (0.64) | CES2CES1L3MBTL1LMNAP4HTM | |
| 2-Picolinic Acid SCHEMBL11378797 | 0.93 | CES2 (0.64) | CES2CES1L3MBTL1LMNAP4HTM | |
| 2-Picolinic Acid SCHEMBL15271681 | 0.93 | CES2 (0.64) | CES2CES1L3MBTL1LMNAP4HTM | |
| 2-Picolinic Acid SCHEMBL5058098 | 0.93 | CES2 (0.64) | CES2CES1L3MBTL1LMNAP4HTM | |
| 2-Picolinic Acid SCHEMBL15401421 | 0.93 | CES2 (0.64) | CES2CES1L3MBTL1LMNAP4HTM | |
| 2-Picolinic Acid SCHEMBL5354659 | 0.93 | CES2 (0.64) | CES2CES1L3MBTL1LMNAP4HTM | |
| 2-Picolinic Acid SCHEMBL432467 | 0.93 | CES2 (0.64) | CES2CES1L3MBTL1LMNAP4HTM | |
| 2-Picolinic Acid SCHEMBL673572 | 0.93 | CES2 (0.64) | CES2CES1L3MBTL1LMNAP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067527-B2 | Thienopyridine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1259515-B1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | TAKEDA PHARMACEUTICAL (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20040054183-A1 | Thienopyridine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| US-6653476-B2 | Antiinflammatory and antiarthritic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-25 | — | — | US | disclosed |
| US-20030130517-A1 | Thienopyridine derivatives , their production and use | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1259515-A2 | THIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001064685-A2 | THIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130517-A1 | Thienopyridine derivatives , their production and use | ALK, HRH2, TBXA2R | CES2 3923/4885CES1 2753/4885L3MBTL1 4725/4885 |
| US-20040054183-A1 | Thienopyridine derivatives, their production and use | ALK, HRH2, TBXA2R | CES2 3923/4885CES1 2753/4885L3MBTL1 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.