Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097443 | 0.92 | CNR2 (0.42) | CNR2NPC1RAB9ATSHRCYP2C8 | |
| SCHEMBL6096840 | 0.85 | CNR2 (0.48) | CNR2NPC1RAB9ACYP2C8CYP2C9 | |
| SCHEMBL6097834 | 0.83 | CNR2 (0.49) | CNR2CYP2C8CYP2C9CYP2C18CYP2C19 | |
| SCHEMBL4443171 | 0.82 | CNR2 (0.45) | CNR2NPC1RAB9ACYP2C8CYP2C9 | |
| SCHEMBL4444967 | 0.80 | CYP1A2 (0.53) | CNR2ARTAS2R14CNR1 | |
| SCHEMBL1624402 | 0.78 | PTGER4 (0.57) | CNR2TAS2R14POLBKEAP1NFE2L2 | |
| SCHEMBL6099551 | 0.77 | HTT (0.47) | CNR2POLBMAPT | |
| SCHEMBL7618745 | 0.76 | PTGER4 (0.54) | CNR2TAS2R14POLBKEAP1NFE2L2 | |
| SCHEMBL7014542 | 0.74 | CNR2 (0.68) | CNR2TSHRTAS2R14POLBCNR1 | |
| SCHEMBL6833587 | 0.74 | CNR2 (0.44) | CNR2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001917-B2 | Pyrazole compounds as anti-inflammatory and analgesic agents | WARNER LAMBERT COMPANY LLC (US) | 2006-02-21 | — | — | US | disclosed |