Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443171 | 0.88 | CNR2 (0.45) | CNR2ALOX5CYP2C8CYP2C9CYP2C18 | |
| SCHEMBL6097834 | 0.87 | CNR2 (0.49) | CNR2ALOX5CYP2C8CYP2C9CYP2C18 | |
| SCHEMBL6097754 | 0.85 | CNR2 (0.49) | CNR2CYP2C8CYP2C9CYP2C18CYP2C19 | |
| SCHEMBL4444967 | 0.80 | CYP1A2 (0.53) | CNR2TAS2R14CNR1TP53 | |
| SCHEMBL6097443 | 0.79 | CNR2 (0.42) | CNR2CYP2C8CYP2C9CYP2C18CYP2C19 | |
| SCHEMBL6098396 | 0.79 | CNR2 (0.43) | CNR2ALOX5CYP2C8CYP2C9CYP2C18 | |
| SCHEMBL6099551 | 0.78 | HTT (0.47) | CNR2POLBTP53MAPTSMN1; SMN2 | |
| SCHEMBL6830539 | 0.77 | LMNA (0.38) | CNR2CYP2C9CYP2C19TAS2R14CNR1 | |
| SCHEMBL6097675 | 0.77 | HSD11B1 (0.44) | CNR2ALOX5CNR1POLBNR3C1 | |
| SCHEMBL6097954 | 0.77 | PTGS2 (0.41) | CNR2ALOX5CYP2C9CYP2C19TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001917-B2 | Pyrazole compounds as anti-inflammatory and analgesic agents | WARNER LAMBERT COMPANY LLC (US) | 2006-02-21 | — | — | US | disclosed |