Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 12/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098436 | 0.99 | CTSA (0.51) | CTSAMMEKIFC1SLC1A3SLC1A2 | |
| SCHEMBL6097767 | 0.98 | CTSA (0.51) | CTSAMMEKIFC1SLC1A3SLC1A2 | |
| SCHEMBL6099049 | 0.93 | CTSA (0.50) | CTSAFFAR1MMP12 | |
| SCHEMBL5927615 | 0.92 | CTSA (0.47) | CTSAMMEKIFC1 | |
| SCHEMBL5926972 | 0.89 | CTSA (0.49) | CTSAMMEKIFC1SLC1A3SLC1A2 | |
| SCHEMBL5926458 | 0.89 | CTSA (0.48) | CTSAMMEKIFC1SLC1A3SLC1A2 | |
| SCHEMBL6100717 | 0.87 | MME (0.49) | CTSAMMEFFAR1WDR5MMP12 | |
| SCHEMBL5927400 | 0.87 | CTSA (0.47) | CTSAMMEKIFC1SLC1A3SLC1A2 | |
| SCHEMBL5927454 | 0.87 | CTSA (0.47) | CTSAMMEKIFC1SLC1A3SLC1A2 | |
| SCHEMBL5927269 | 0.86 | CTSA (0.46) | CTSAMMEKIFC1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |