Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 5/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926600 | 0.91 | MME (0.42) | MMEMMP12FFAR1WDR5CTSA | |
| SCHEMBL6099049 | 0.90 | CTSA (0.50) | MMP12FFAR1CTSA | |
| SCHEMBL6097767 | 0.89 | CTSA (0.51) | MMEFFAR1CTSA | |
| SCHEMBL6098336 | 0.88 | MMP12 (0.60) | MMEMMP12CTSAITGB3ITGAV | |
| SCHEMBL6100609 | 0.88 | MMP12 (0.48) | MMEMMP12FFAR1CTSAITGB3 | |
| SCHEMBL6097852 | 0.87 | CTSA (0.52) | MMEMMP12FFAR1WDR5CTSA | |
| SCHEMBL6098436 | 0.86 | CTSA (0.51) | MMEMMP12FFAR1CTSA | |
| SCHEMBL6100710 | 0.84 | KIFC1 (0.56) | MMESLC13A5 | |
| SCHEMBL6095745 | 0.84 | CYP26A1 (0.48) | MMEFFAR1CTSA | |
| SCHEMBL5926414 | 0.83 | TACR3 (0.50) | FFAR1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |