Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 9/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597641 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2PTGDR2TSHRHTR2AHTR2C | |
| SCHEMBL2210931 | 0.88 | TSHR (0.66) | SMN1; SMN2PTGDR2TSHRHTR2AHTR2C | |
| SCHEMBL2597640 | 0.88 | TSHR (0.66) | SMN1; SMN2PTGDR2TSHRHTR2AHTR2C | |
| SCHEMBL11212441 | 0.86 | POLB (0.63) | SMN1; SMN2PTGDR2TSHRHTR2AHTR2C | |
| SCHEMBL8853494 | 0.85 | TSHR (0.55) | SMN1; SMN2PTGDR2TSHRHTR2AHTR2C | |
| SCHEMBL8935907 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2PTGDR2TSHRHTR2BPPARA | |
| SCHEMBL8935915 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2PTGDR2TSHRHTR2BPPARA | |
| Dimethylamine SCHEMBL28258492 | 0.84 | TSHR (0.61) | SMN1; SMN2PTGDR2TSHRHTR2AHTR2C | |
| SCHEMBL9780844 | 0.83 | PPARA (0.68) | SMN1; SMN2PTGDR2TSHRHTR2AHTR2C | |
| SCHEMBL541271 | 0.83 | PPARA (0.68) | SMN1; SMN2PTGDR2TSHRHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101448776-A | Glyceride ester derivatives of herbicidal compounds and compositions thereof | NUFARM AUSTRALIA LTD (AU) | 2009-06-03 | — | — | CN | claimed |
| CN-114867350-A | Low volatility polyamine salts of anionic pesticides | 巴斯夫公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-101448776-A | Glyceride ester derivatives of herbicidal compounds and compositions thereof | NUFARM AUSTRALIA LTD (AU) | 2009-06-03 | — | — | CN | disclosed |
| US-7002020-B1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | PHARMACIA & UPJOHN COMPANY (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050004174-A1 | Antibacterial agents | GORDEEV MIKHAIL F (US) | 2005-01-06 | — | — | US | disclosed |
| US-6562844-B2 | Attaching an olefin to a solid support; oxidizing the olefin to provide an epoxide functionality; opening the epoxide with an amine to form an amino alcohol; cyclizing the amino alcohol using a phosgene equivalent | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |
| US-6531470-B1 | Antimicrobial compounds | PHARMACIA & UPJOHN COMPANY | 2003-03-11 | — | — | US | disclosed |
| EP-1049682-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | Versicor, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037630-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | VERSICOR, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004174-A1 | Antibacterial agents | PAICS, OXA1L, PNKP | SMN1; SMN2 202/4885PTGDR2 3979/4885TSHR 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.