SCHEMBL6098547

SCHEMBL6098547

O=C(O)Cc1ccc2oc(-c3nc(C4CCCCC4)[nH]c3COC34CC5CC(CC(C5)C3)C4)nc2c1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 1/20 0.48
HPSE Q9Y251 13/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6094324 0.89 CCKBR (0.57) CCKBR
SCHEMBL6097770 0.85 CCKBR (0.49) CCKBRKDM4E
SCHEMBL6096491 0.84 CCKBR (0.57) CCKBR
SCHEMBL6339248 0.74 CCKBR (0.61) CCKBRKDM4E
SCHEMBL6332196 0.73 CCKBR (0.52) CCKBR
SCHEMBL6160431 0.73 CCKBR (0.79) CCKBR
SCHEMBL6160236 0.73 CCKBR (0.79) CCKBR
SCHEMBL7115482 0.73 CCKBR (0.51) CCKBR
SCHEMBL6334200 0.72 CCKBR (0.60) CCKBR
SCHEMBL6094542 0.72 CCKBR (0.58) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7034048-B2 Gastrin and cholecystokinin receptor ligands (III) JAMES BLACK FOUNDATION LIMITED (GB) 2006-04-25 US disclosed
US-20030191116-A1 Gastrin and cholecystokinin receptor ligands (III) JAMES BLACK FOUNDATION LIMITED (GB) 2003-10-09 US disclosed
WO-2001085724-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS (III) JAMES BLACK FOUNDATION LIMITED (GB) 2001-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191116-A1 Gastrin and cholecystokinin receptor ligands (III) CCKAR, CCKBR, GRPR CCKBR 2/4885HPSE 1309/4885KDM4E 4777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.