Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097691 | 0.84 | MEN1 (0.61) | ALDH1A1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL6097688 | 0.84 | MEN1 (0.61) | ALDH1A1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL12316834 | 0.73 | KMT2A (0.82) | ALDH1A1NPSR1L3MBTL1KMT2ATP53 | |
| SCHEMBL3424682 | 0.73 | APAF1 (0.54) | ALDH1A1L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL6098152 | 0.72 | MEN1 (0.58) | ALDH1A1KMT2ATDP1TP53LMNA | |
| SCHEMBL6098154 | 0.72 | MEN1 (0.58) | ALDH1A1KMT2ATDP1TP53LMNA | |
| SCHEMBL11746111 | 0.72 | MAPT (0.53) | L3MBTL1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL11746100 | 0.72 | MAPT (0.53) | L3MBTL1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL11699510 | 0.71 | POLB (0.70) | ALDH1A1L3MBTL1LMNAPOLBMAPT | |
| SCHEMBL12316851 | 0.68 | KMT2A (0.86) | ALDH1A1NPSR1L3MBTL1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053216-B2 | Modulators of Rho C activity | ICONIX PHARMACEUTICALS, INC. (US) | 2006-05-30 | — | — | US | disclosed |