Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.42 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 1/20 | 0.41 |
| ▸ | SDHA | P31040 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358452 | 0.89 | MAOB (0.44) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5404120 | 0.84 | MAOB (0.46) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6098395 | 0.84 | MAOB (0.43) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5386209 | 0.80 | MAOB (0.60) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5387972 | 0.79 | MAOB (0.41) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5395913 | 0.78 | CALML3 (0.55) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5390962 | 0.78 | MAOB (0.49) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6098319 | 0.77 | MAOB (0.44) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5395906 | 0.77 | MAOA (0.70) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL14580205 | 0.76 | MAOB (0.57) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030148-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2006-04-18 | — | — | US | disclosed |