SCHEMBL609886

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10235883	0.88	CYP2D6 (0.48)	GGPS1CYP2D6KCNH2TSHRMAPK1
	SCHEMBL612001	0.85	TAAR1 (0.47)	TAAR1GGPS1ACHEKCNH2CYP4F2
	SCHEMBL611253	0.82	TAAR1 (0.45)	TAAR1GGPS1ACHECYP2D6KCNH2
	SCHEMBL612432	0.81	GGPS1 (0.44)	TAAR1GGPS1ACHECYP2D6KCNH2
	SCHEMBL10258364	0.81	TAAR1 (0.44)	TAAR1GGPS1ACHECYP2D6KCNH2
	SCHEMBL3836970	0.81	GGPS1 (0.42)	TAAR1GGPS1CYP2D6LTA4HTSHR
	SCHEMBL610311	0.79	GGPS1 (0.48)	TAAR1GGPS1CYP2D6KCNH2TSHR
	SCHEMBL26850251	0.79	TAAR1 (0.50)	TAAR1ACHECYP2D6KCNH2LTA4H
	SCHEMBL610502	0.79	TAAR1 (0.39)	TAAR1
	SCHEMBL16802388	0.78	TAAR1 (0.46)	TAAR1GGPS1ACHEKCNH2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.