Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.57 |
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690900 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2B | |
| SCHEMBL7294041 | 0.85 | ITGB3 (0.78) | ITGB3ITGA2BCCR1 | |
| SCHEMBL8379088 | 0.85 | ITGB3 (0.78) | ITGB3ITGA2BCCR1 | |
| SCHEMBL8643931 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BCCR1 | |
| SCHEMBL6099449 | 0.84 | ITGB3 (0.75) | ITGB3ITGA2B | |
| SCHEMBL4425018 | 0.84 | ITGB3 (0.75) | ITGB3ITGA2B | |
| SCHEMBL8692845 | 0.84 | ITGB3 (0.74) | ITGB3ITGA2B | |
| SCHEMBL7291927 | 0.82 | ITGB3 (0.62) | ITGB3ITGA2B | |
| SCHEMBL8690974 | 0.81 | ITGB3 (0.58) | ITGB3ITGA2BCCR1 | |
| SCHEMBL8690912 | 0.79 | ITGB3 (0.53) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109326-B2 | Halo-alkoxycarbonyl prodrugs | GENENTECH, INC. (US) | 2006-09-19 | — | — | US | disclosed |
| EP-0975608-B1 | HALO-ALKOXYCARBONYL PRODRUGS | GENENTECH INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040220401-A1 | Novel halo-alkoxycarbonyl prodrugs | GENENTECH, INC. | 2004-11-04 | — | — | US | disclosed |
| US-20010020019-A1 | NOVEL HALO-ALKOXYCARBONYL PRODRUGS | GENENTECH, INC. | 2001-09-06 | — | — | US | disclosed |
| EP-0975608-A2 | HALO-ALKOXYCARBONYL PRODRUGS | Genentech, Inc. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046576-A2 | HALO-ALKOXYCARBONYL PRODRUGS | GENENTECH, INC. (US) | 1998-10-22 | — | — | WO | disclosed |
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220401-A1 | Novel halo-alkoxycarbonyl prodrugs | PNP, PAICS, PHOSPHO1 | ITGB3 2194/4885ITGA2B 3070/4885CCR1 1250/4885 |
| US-20010020019-A1 | NOVEL HALO-ALKOXYCARBONYL PRODRUGS | PNP, PAICS, PHOSPHO1 | ITGB3 2194/4885ITGA2B 3070/4885CCR1 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.