SCHEMBL610013

SCHEMBL610013

CC1(C)c2ccccc2NC12C=Cc1cc([N+](=O)[O-])ccc1O2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.43
KMT2A Q03164 7/20 0.43
MAPT P10636 5/20 0.43
GFER P55789 1/20 0.42
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALPL P05186 1/20 0.39
HTT P42858 1/20 0.39
HIF1A Q16665 5/20 0.39
EPAS1 Q99814 5/20 0.39
CA9 Q16790 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
GAA P10253 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
LMNA P02545 1/20 0.37
ALPG P10696 1/20 0.37
RECQL P46063 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466096 1.00 MEN1 (0.43) MEN1KMT2AMAPTGFERALDH1A1
SCHEMBL29633966 1.00 MEN1 (0.43) MEN1KMT2AMAPTGFERALDH1A1
SCHEMBL14399560 0.86 MEN1 (0.41) MEN1KMT2AMAPTGFERALDH1A1
SCHEMBL27100749 0.84 MEN1 (0.47) MEN1KMT2AMAPTGFERALDH1A1
SCHEMBL17342555 0.84 SNCA (0.45) MEN1KMT2AMAPTGFERALDH1A1
SCHEMBL23702608 0.82 MAPK1 (0.41) MEN1KMT2AMAPTGFERALDH1A1
SCHEMBL27100756 0.82 MEN1 (0.51) MEN1KMT2AMAPTGFERALDH1A1
SCHEMBL17342556 0.81 NPSR1 (0.43) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL16270944 0.81 GAA (0.36) MEN1KMT2AMAPTHIF1AEPAS1
SCHEMBL19000228 0.80 HTR2C (0.40) MEN1KMT2AMAPTHTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738728-A2 Ionic spiropyran compound and photochromic material conjugated it with clay NISSHO IWAI BENTONITE CO.,LTD. (JP) 1996-10-23 EP claimed
JP-61018782-A None JP disclosed
JP-8291176-A None JP disclosed
US-8236466-B2 Photochromic materials incorporated in polymer backbone XEROX CORPORATION (US) 2012-08-07 US disclosed
US-20120038718-A1 STABILIZED PHOTOCHROMIC INK FOR REUSABLE PAPER ANNOTATION XEROX CORPORATION (US) 2012-02-16 US disclosed
US-20110082035-A1 PHOTOCHROMIC MATERIALS INCORPORATED IN POLYMER BACKBONE XEROX CORPORATION (US) 2011-04-07 US disclosed
US-7782732-B2 Optical recording method, optical reproducing method, and optical reproducing apparatus FUJI XEROX CO., LTD. (JP) 2010-08-24 US disclosed
US-7300727-B2 Method for forming temporary image XEROX CORPORATION (US) 2007-11-27 US disclosed
US-20070236763-A1 Optical recording method, optical reproducing method, and optical reproducing apparatus FUJI XEROX CO., LTD. (JP) 2007-10-11 US disclosed
US-7202006-B2 Protective layer for reimageable medium XEROX CORPORATION (US) 2007-04-10 US disclosed
US-20070003847-A1 Protective layer for reimageable medium XEROX CORPORATION 2007-01-04 US disclosed
JP-H08291176-A IONIC SPIROPYRAN COMPOUNDS AND PHOTOCHROMIC MATERIAL CONTAINING THE SAME COMPOUNDED WITH CLAY NISSHO IWAI BENTONAITO KK 1996-11-05 JP disclosed
EP-0738728-A2 Ionic spiropyran compound and photochromic material conjugated it with clay NISSHO IWAI BENTONITE CO.,LTD. (JP) 1996-10-23 EP disclosed
JP-S6118782-A 3,3-DIMETHYL-6'-NITROSPIRO(INDOLINE-2,2'-2H-BENZOPYRAN) DERIVATIVE MITSUBISHI CHEM IND LTD 1986-01-27 JP disclosed
JP-S06118782-A 0001-01-01 JP disclosed