Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101314 | 0.90 | KMT2A (0.55) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL6100235 | 0.80 | BCHE (0.65) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL6101976 | 0.79 | SNCA (0.64) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL6100957 | 0.79 | GAA (0.52) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL6101972 | 0.79 | SNCA (0.64) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL2925120 | 0.78 | TRPV1 (0.70) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL6099937 | 0.77 | ALDH1A1 (0.65) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL6099398 | 0.77 | KMT2A (0.64) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL14298826 | 0.77 | GAA (0.69) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL19879879 | 0.76 | HPGD (0.60) | GAAALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1282640-C | N-arylphenylacetamide derivatives and medicinal compositions containing same | DAINIPPON PHARMACEUTICAL CO (JP) | 2006-11-01 | — | — | CN | disclosed |
| US-7084176-B2 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |
| US-20040248983-A1 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| CN-1529692-A | N-arylphenylacetamide derivatives and medicinal compositions containing same | 大日本制药株式会社 | 2004-09-15 | — | — | CN | disclosed |
| EP-1403235-A1 | N-ARYLPHENYLACETAMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248983-A1 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | HRH2, CCR8, CYP2C8 | GAA 4362/4885ALDH1A1 684/4885TSHR 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.