Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 8/20 | 0.47 |
| ▸ | CTSA | P10619 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926904 | 0.93 | CTSA (0.50) | CYP26A1CTSAMEN1KMT2A | |
| SCHEMBL5926699 | 0.88 | CTSA (0.42) | CYP26A1CTSAMEN1KMT2A | |
| SCHEMBL3978076 | 0.88 | EGLN2 (0.47) | CYP26A1CTSAMEN1KMT2AHPGD | |
| SCHEMBL5926915 | 0.86 | TACR3 (0.41) | CYP26A1CTSAMEN1KMT2A | |
| SCHEMBL3992039 | 0.86 | CTSA (0.44) | CYP26A1CTSAGCGR | |
| SCHEMBL6101133 | 0.85 | ITGB1 (0.44) | MEN1KMT2A | |
| SCHEMBL5926316 | 0.84 | CNR1 (0.42) | CYP26A1CTSAMEN1KMT2A | |
| SCHEMBL5926299 | 0.83 | CTSA (0.43) | CYP26A1CTSAMEN1KMT2A | |
| SCHEMBL5926161 | 0.83 | CASP3 (0.42) | CTSAKMT2A | |
| SCHEMBL5926269 | 0.82 | CTSA (0.41) | CTSAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |