Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748186 | 0.89 | PTGS1 (0.61) | PTGS1PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1902083 | 0.85 | LTA4H (0.65) | PTGS1PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14467536 | 0.83 | PTGS1 (0.61) | PTGS1PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10729452 | 0.83 | PTGS1 (0.61) | PTGS1PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10158221 | 0.83 | PTGS1 (0.61) | PTGS1PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL72049 | 0.83 | PTGS1 (0.61) | PTGS1PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10090420 | 0.83 | PTGS1 (0.61) | PTGS1PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9167195 | 0.81 | PTGS1 (0.64) | PTGS1PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14688967 | 0.81 | PTGS1 (0.60) | PTGS1PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10090168 | 0.81 | PTGS1 (0.64) | PTGS1PTGS2SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028464-B | Antarctic fungus secondary metabolism derivative BTZ-one and preparation method and application thereof | 浙江海洋大学 | 2022-11-18 | — | — | CN | claimed |
| CN-110028464-B | Antarctic fungus secondary metabolism derivative BTZ-one and preparation method and application thereof | 浙江海洋大学 | 2022-11-18 | — | — | CN | disclosed |
| WO-2013054338-A1 | 2-THIO-IMIDAZOLE DERIVATIVES AS TGR5 MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2013-04-18 | — | — | WO | disclosed |
| WO-2007081091-A1 | RHODANDSE DERIVARIVES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-07-19 | — | — | WO | disclosed |
| US-20060281736-A1 | Product comprising at least one phosphatase cdc25 inhibitor combined with at least one other anticancer agent | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281736-A1 | Product comprising at least one phosphatase cdc25 inhibitor combined with at least one other anticancer agent | CDC25A, CDC25C, CDC25B | PTGS1 2925/4885PTGS2 3022/4885SMN1; SMN2 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.