SCHEMBL610168

SCHEMBL610168

C=C(C)c1cccc(N(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
TSHR P16473 2/20 0.52
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.45
KDM4E B2RXH2 7/20 0.44
MAPT P10636 5/20 0.44
HPGD P15428 4/20 0.44
HSD17B10 Q99714 4/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GFER P55789 1/20 0.44
MAPK1 P28482 1/20 0.41
ALOX15 P16050 2/20 0.41
RAF1 P04049 1/20 0.40
TP53 P04637 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28097745 0.81 ALDH1A1 (0.38) ALDH1A1TSHRKMT2AMEN1L3MBTL1
SCHEMBL609636 0.80 KMT2A (0.69) ALDH1A1TSHRKMT2AMEN1L3MBTL1
SCHEMBL167439 0.79 FURIN (0.43) TSHRL3MBTL1LMNAMAPTTDP1
SCHEMBL334924 0.79 KDM4E (0.56) ALDH1A1TSHRKMT2AL3MBTL1LMNA
SCHEMBL17191013 0.79 ALDH1A1 (0.52) ALDH1A1TSHRKMT2AL3MBTL1LMNA
SCHEMBL608324 0.79 HTT (0.34) ALDH1A1TSHRKMT2AMEN1L3MBTL1
SCHEMBL608842 0.79 ALDH1A1 (0.56) ALDH1A1TSHRKMT2AMEN1L3MBTL1
SCHEMBL10473921 0.79 KMT2A (0.72) ALDH1A1TSHRKMT2AMEN1L3MBTL1
SCHEMBL611180 0.78 PTPN1 (0.45) ALDH1A1TSHRKMT2AL3MBTL1KDM4E
SCHEMBL15624321 0.78 ALDH1A1 (0.50) ALDH1A1TSHRKMT2AL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11180657-B2 Polysulfonated fluorescence dyes ATTO-TEC GMBH (DE) 2021-11-23 US disclosed
EP-3461815-B1 NOVEL POLY SULFONATED FLUORESCENCE DYES ATTO TEC GMBH (DE) 2021-03-03 EP disclosed
EP-3461815-B1 NOVEL POLY SULFONATED FLUORESCENCE DYES ATTO TEC GMBH (DE) 2021-03-03 EP disclosed
EP-3239183-B1 MODIFIED CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION CONTAINING SAID POLYMER SUMITOMO CHEMICAL CO (JP) 2020-03-11 EP disclosed
US-20190322870-A2 NOVEL POLYSULFONATED FLUORESCENCE DYES ATTO-TEC GMBH (DE) 2019-10-24 US disclosed
US-20190100653-A1 NOVEL POLYSULFONATED FLUORESCENCE DYES ATTO-TEC GMBH (DE) 2019-04-04 US disclosed
US-20190100653-A1 NOVEL POLYSULFONATED FLUORESCENCE DYES ATTO-TEC GMBH (DE) 2019-04-04 US disclosed
EP-3461815-A1 NOVEL POLY SULFONATED FLUORESCENCE DYES ATTO-TEC GmbH (DE) 2019-04-03 EP disclosed
EP-3461814-A1 NEW POLYSULFONATED FLUORESCENT DYES ATTO-TEC GmbH (DE) 2019-04-03 EP disclosed
EP-3461815-A1 NOVEL POLY SULFONATED FLUORESCENCE DYES ATTO-TEC GmbH (DE) 2019-04-03 EP disclosed
US-6828159-B1 Carbopyronine fluorescent dyes Drexhage, Karl-Heinz (DE) 2004-12-07 US disclosed
US-20040142137-A1 Fast-writable and precision-writable high-capacity optical storage media CIBA SPECIALTY CHEMICALS CORP. 2004-07-22 US disclosed
EP-1412942-A1 FAST-WRITABLE AND PRECISION-WRITABLE HIGH-CAPACITY OPTICAL STORAGE MEDIA Ciba SC Holding AG (CH) 2004-04-28 EP disclosed
EP-1173519-B1 NOVEL CARBOPYRONINE FLUORESCENCE DYES DREXHAGE KARL-HEINZ (DE) 2003-08-20 EP disclosed
WO-2003007296-A1 FAST-WRITABLE AND PRECISION-WRITABLE HIGH-CAPACITY OPTICAL STORAGE MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-01-23 WO disclosed
EP-1173519-A1 NOVEL CARBOPYRONINE FLUORESCENCE DYES DREXHAGE, Karl-Heinz (DE) 2002-01-23 EP disclosed
WO-2000064986-A1 NOVEL CARBOPYRONINE FLUORESCENCE DYES DREXHAGE KARL HEINZ (DE) 2000-11-02 WO disclosed
US-4535052-A HIGH SPEED PHOTORESISTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-13 US disclosed
EP-0127762-A1 Constrained N-alkylamino aryl ketones as sensitizers for photopolymer compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-12-12 EP disclosed
US-3980706-A Synthesis of 2,7-bisdimethylamino-10-P-dimethylaminophenyl-9,10-dihydro-9,9-dimethylanthracene HORIZONS INCORPORATED A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) 1976-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11180657-B2 Polysulfonated fluorescence dyes CD44, ARSA, STS ALDH1A1 199/4885TSHR 4164/4885KMT2A 3911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.