Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.90 |
| ▸ | MEN1 | O00255 | 5/20 | 0.90 |
| ▸ | LMNA | P02545 | 5/20 | 0.90 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.90 |
| ▸ | GMNN | O75496 | 1/20 | 0.90 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.90 |
| ▸ | POLB | P06746 | 1/20 | 0.90 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.90 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.90 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.90 |
| ▸ | HPGD | P15428 | 1/20 | 0.90 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.90 |
| ▸ | TSHR | P16473 | 1/20 | 0.90 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.90 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.90 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.90 |
| ▸ | THPO | P40225 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708863 | 1.00 | MAPT (0.90) | MAPTKMT2AMEN1LMNAALOX12 | |
| Capsazepine SCHEMBL122421 | 0.95 | KMT2A (1.00) | MAPTKMT2AMEN1LMNAALOX12 | |
| Capsazepine SCHEMBL29570456 | 0.95 | KMT2A (1.00) | MAPTKMT2AMEN1LMNAALOX12 | |
| SCHEMBL5708740 | 0.94 | KMT2A (0.78) | MAPTKMT2AMEN1LMNAALOX12 | |
| SCHEMBL5708706 | 0.94 | KMT2A (0.78) | MAPTKMT2AMEN1LMNAALOX12 | |
| SCHEMBL31657800 | 0.88 | KMT2A (0.87) | MAPTKMT2AMEN1LMNAALOX12 | |
| SCHEMBL5708818 | 0.88 | MAPT (0.69) | MAPTKMT2AMEN1LMNAALOX12 | |
| SCHEMBL5708805 | 0.88 | KMT2A (0.87) | MAPTKMT2AMEN1LMNAALOX12 | |
| SCHEMBL5334297 | 0.87 | MEN1 (0.81) | MAPTKMT2AMEN1LMNAALOX12 | |
| SCHEMBL5708804 | 0.87 | MAPT (0.82) | MAPTKMT2AMEN1LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060040919-A1 | Bronchorelaxing compounds | RESPIRATORIUS AB (SE) | 2006-02-23 | — | — | US | disclosed |
| US-20050165004-A1 | Bronchorelaxing compounds | RESPIRATORIUS AB (SE) | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165004-A1 | Bronchorelaxing compounds | GPR6, CHRM3, NR1H3 | MAPT 4611/4885KMT2A 3030/4885MEN1 1409/4885 |
| US-20060040919-A1 | Bronchorelaxing compounds | CHRM3, GPR3, CHRM2 | MAPT 4617/4885KMT2A 3875/4885MEN1 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.