Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6100655 | 0.90 | PTGIR (0.51) | PTGIRPTGDRTBXA2R | |
| SCHEMBL6101497 | 0.89 | PTGIR (0.50) | PTGIR | |
| SCHEMBL2190959 | 0.84 | PTGIR (0.60) | PTGIRPTGDRTBXA2R | |
| SCHEMBL6102794 | 0.77 | PTGIR (0.79) | PTGIRPTGDRTBXA2R | |
| SCHEMBL730460 | 0.77 | PTGIR (0.64) | PTGIRPTGDR | |
| SCHEMBL2191851 | 0.77 | PTGIR (0.64) | PTGIRPTGDR | |
| SCHEMBL2189965 | 0.77 | PTGIR (0.64) | PTGIRPTGDRTBXA2R | |
| SCHEMBL731003 | 0.76 | PTGDR (0.62) | PTGIRPTGDR | |
| SCHEMBL2193189 | 0.75 | PTGIR (0.62) | PTGIRPTGDRTBXA2R | |
| SCHEMBL730628 | 0.74 | PTGIR (0.63) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089353-A1 | Indole derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-04-27 | — | — | US | disclosed |
| EP-1600440-A1 | INDOLE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089353-A1 | Indole derivative compounds and drugs containing the compounds as the active ingredient | PTGIS, IDO1, IDO2 | PTGIR 4/4885PTGDR 11/4885TBXA2R 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.