Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 5/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 6/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 5/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4239286 | 0.88 | RIPK1 (0.43) | RIPK1MAOBADORA2AADORA2BADORA1 | |
| SCHEMBL4242677 | 0.86 | RIPK1 (0.42) | RIPK1MAOBADORA2AADORA2BADORA1 | |
| SCHEMBL4240686 | 0.83 | RIPK1 (0.44) | RIPK1MAOBADORA2AADORA2BADORA1 | |
| SCHEMBL4236063 | 0.81 | DHODH (0.60) | MAOBADORA2AADORA2BADORA1DHODH | |
| SCHEMBL4243794 | 0.80 | DHODH (0.48) | MAOBADORA2AADORA2BADORA1DHODH | |
| SCHEMBL4239818 | 0.78 | DHODH (0.57) | MAOBADORA2AADORA2BADORA1DHODH | |
| SCHEMBL1202261 | 0.78 | MAOB (0.51) | MAOBADORA2AADORA2BADORA1DHODH | |
| SCHEMBL1202540 | 0.78 | ABL1 (0.41) | RIPK1MAOBADORA2AADORA2BADORA1 | |
| SCHEMBL1201634 | 0.76 | RIPK1 (0.40) | RIPK1MAOBADORA2AADORA2BADORA1 | |
| SCHEMBL4244341 | 0.76 | MAOB (0.48) | MAOBADORA2AADORA2BADORA1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223849-A1 | Benzazole derivatives, compositions, and methods of use as beta-secretase inhibitors | HIGH POINT PHARMACEUTICALS, LLC | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223849-A1 | Benzazole derivatives, compositions, and methods of use as beta-secretase inhibitors | BACE1, BACE2, APP | RIPK1 3079/4885MAOB 269/4885ADORA2A 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.