Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 5/20 | 0.38 |
| ▸ | HTR1B | P28222 | 5/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 2/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6100449 | 0.89 | HTR1D (0.39) | HTR1DHTR1B | |
| SCHEMBL6099612 | 0.83 | HTR1D (0.55) | HTR1DHTR1BFFAR2GHSR | |
| SCHEMBL6100571 | 0.81 | GHSR (0.41) | HTR1DHTR1BGHSR | |
| SCHEMBL6100069 | 0.78 | HTR1D (0.44) | HTR1DHTR1BGHSR | |
| SCHEMBL6166896 | 0.78 | HTR1D (0.44) | HTR1DHTR1BGHSR | |
| SCHEMBL6101456 | 0.76 | HTR1D (0.41) | HTR1DHTR1B | |
| SCHEMBL6099761 | 0.74 | HTR1D (0.68) | HTR1DHTR1BGHSR | |
| SCHEMBL6101634 | 0.72 | HTR1D (0.57) | HTR1DHTR1B | |
| SCHEMBL6102080 | 0.70 | HTR1D (0.59) | HTR1DHTR1BFFAR2GHSR | |
| SCHEMBL6102088 | 0.69 | HTR1D (0.42) | HTR1DHTR1BGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109201-B2 | Piperazine derivatives, their preparation and uses in therapy | SMITHKLINE BEECHAM PLC (GB) | 2006-09-19 | — | — | US | claimed |