Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.69 |
| ▸ | HTR1A | P08908 | 17/20 | 0.69 |
| ▸ | HTR2A | P28223 | 17/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375822 | 0.91 | DRD2 (0.77) | DRD2HTR1AHTR2A | |
| SCHEMBL6102016 | 0.88 | DRD2 (0.82) | DRD2HTR1AHTR2A | |
| SCHEMBL3399727 | 0.87 | DRD2 (0.75) | DRD2HTR1AHTR2A | |
| SCHEMBL6101956 | 0.86 | DRD2 (0.68) | DRD2HTR1AHTR2A | |
| SCHEMBL252469 | 0.85 | DRD2 (0.72) | DRD2HTR1AHTR2A | |
| SCHEMBL253668 | 0.85 | DRD2 (0.77) | DRD2HTR1AHTR2A | |
| SCHEMBL5366833 | 0.85 | DRD2 (0.82) | DRD2HTR1AHTR2A | |
| SCHEMBL5379276 | 0.83 | DRD2 (0.82) | DRD2HTR1AHTR2A | |
| SCHEMBL5371757 | 0.83 | DRD2 (0.73) | DRD2HTR1AHTR2A | |
| SCHEMBL5369038 | 0.82 | DRD2 (0.81) | DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006090272-A1 | ISOQUINOLINE [1,8]NAPHTHYRIDIN-2-ONES AND RELATED COMPOUNDS FOR TREATMENT OF SCHIZOPHRENIA | WARNER-LAMBERT COMPANY LLC (US) | 2006-08-31 | — | — | WO | claimed |
| WO-2006090272-A1 | ISOQUINOLINE [1,8]NAPHTHYRIDIN-2-ONES AND RELATED COMPOUNDS FOR TREATMENT OF SCHIZOPHRENIA | WARNER-LAMBERT COMPANY LLC (US) | 2006-08-31 | — | — | WO | disclosed |