SCHEMBL6103464

SCHEMBL6103464

CCC[C@@H](NC(=O)Nc1ccc(Cl)s1)C(=O)Nc1ccc(N2CCOCC2=O)cc1

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6103469 1.00 F10 (0.78) F10
SCHEMBL6105641 0.90 F10 (0.72) F10
SCHEMBL6105634 0.90 F10 (0.72) F10
SCHEMBL6103778 0.89 F10 (0.62) F10
SCHEMBL6103783 0.89 F10 (0.62) F10
SCHEMBL6106848 0.88 F10 (0.79) F10
SCHEMBL6106840 0.88 F10 (0.79) F10
SCHEMBL4029786 0.87 F10 (1.00) F10
SCHEMBL4030521 0.87 F10 (1.00) F10
SCHEMBL6105426 0.87 F10 (0.58) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060135515-A1 Heterocyclic amides and their use treating thromboembolic diseases and tumors MERCK PATENT GMBH (DE) 2006-06-22 — — US claimed
US-20060135515-A1 Heterocyclic amides and their use treating thromboembolic diseases and tumors MERCK PATENT GMBH (DE) 2006-06-22 — — US disclosed
WO-2004035039-A1 HETEROCYCLIC AMIDES AND THEIR USE IN TREATING THROMBOEMBOLIC DISEASES AND TUMORS MERCK PATENT GMBH (DE) 2004-04-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060135515-A1 Heterocyclic amides and their use treating thromboembolic diseases and tumors F2, F11, F12 F10 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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