Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.43 |
| ▸ | CTSL | P07711 | 6/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107436 | 0.90 | CTSS (0.44) | CTSSCTSLCTSK | |
| SCHEMBL5364909 | 0.87 | CTSS (0.57) | CTSSCTSL | |
| SCHEMBL5364916 | 0.87 | CTSS (0.57) | CTSSCTSL | |
| SCHEMBL6107306 | 0.87 | CTSS (0.44) | CTSSCTSLCTSK | |
| SCHEMBL6105630 | 0.86 | CTSS (0.43) | CTSSCTSLCTSK | |
| SCHEMBL6108168 | 0.85 | CTSS (0.42) | CTSSCTSLCTSK | |
| SCHEMBL6108160 | 0.85 | CTSS (0.42) | CTSSCTSLCTSK | |
| SCHEMBL6106965 | 0.83 | CTSS (0.52) | CTSSCTSLCTSK | |
| SCHEMBL7478292 | 0.82 | CTSS (0.53) | CTSSCTSLCTSK | |
| SCHEMBL6107448 | 0.78 | CTSS (0.44) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982272-B2 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | disclosed |