Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6108430 | 0.92 | DPP4 (0.49) | DPP4 | |
| SCHEMBL6108595 | 0.91 | DPP4 (0.42) | DPP4KDM4EKMT2A | |
| SCHEMBL6106220 | 0.89 | DPP4 (0.45) | DPP4 | |
| SCHEMBL6107516 | 0.89 | DPP4 (0.41) | DPP4 | |
| SCHEMBL6108026 | 0.89 | DPP4 (0.43) | DPP4KDM4EKMT2ARXRA | |
| SCHEMBL6109497 | 0.89 | DPP4 (0.50) | DPP4HPGDKDM4EKMT2A | |
| SCHEMBL6107740 | 0.88 | PGR (0.39) | DPP4 | |
| SCHEMBL6108201 | 0.88 | DPP4 (0.39) | DPP4 | |
| SCHEMBL6108025 | 0.88 | DPP4 (0.44) | DPP4KDM4EKMT2A | |
| SCHEMBL6107876 | 0.87 | DPP4 (0.43) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |